UniProt Accession

 MI4GD_HUMAN; A9UHW6; B4DUM7; Q8N4Q5; Q9HBL5 

Genbank Protein ID

 EU287989; AL555095; AK300711; AC022211; CH471099; BC033759; AF225422 

Genbank Nucleotide ID

 ABX83907.1; BAG62389.1; EAW89263.1; AAH33759.1; AAG09724.1 

Protein Name

 MIF4G domain-containing protein 

Protein Synonyms/Alias

 SLBP-interacting protein 1; hSLIP1 

Gene Name

 MIF4GD 

Gene Synonyms/Alias

 SLIP1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
10	EPSREEYKIQSFDAE	ubiquitination	[1]
23	AETQQLLKTALKDPG	ubiquitination	[1]
27	QLLKTALKDPGAVDL	ubiquitination	[1]
53	LQDCVFSKEAGRMCY	acetylation	[2]
53	LQDCVFSKEAGRMCY	ubiquitination	[1, 2]
68	AIIQAESKQAGQSVF	ubiquitination	[2]
214	KTTPAAHKYYYSEVS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation. 

Sequence Annotation

 DOMAIN 3 205 MIF4G.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Translation regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 222 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
 GO:0016070; P:RNA metabolic process; IEA:InterPro. 

Interpro

 IPR016024; ARM-type_fold.
 IPR016021; MIF4-like_typ_1/2/3.
 IPR003890; MIF4G-like_typ-3. 

Pfam

 PF02854; MIF4G 

SMART

  

PROSITE

  

PRINTS