CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005380
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LAS seventeen-binding protein 5 
Protein Synonyms/Alias
 LAS17-binding protein 5 
Gene Name
 LSB5 
Gene Synonyms/Alias
 YCL034W; YCL186; YCL34W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
115ENSGSGEKYEPRIIKubiquitination[1]
157YQLGQTVKQRYSKSSubiquitination[1]
210IPQINMNKEAPRIRLubiquitination[1]
251DDEEATSKFIQARAIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with YSC84. 
Sequence Annotation
 DOMAIN 15 161 VHS.  
Keyword
 Complete proteome; Cytoplasm; Cytoskeleton; Endocytosis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 354 AA 
Protein Sequence
MGFLSDHPHT AITETIFRIV SSRDYTLEVE LAPLIQLIKA DHNDYNYTVN QEEAARALRK 60
KIKYGNRLQQ SRTLDLLDLF ISQGVKFTVM YNDDKLLQRL RGMATNSENS GSGEKYEPRI 120
IKKCAAYAIS WLNYITQNNL ENARAYSGLY QLGQTVKQRY SKSSRSRRSG GGSGGRSNFM 180
DDSADDTLYQ SNSLTSADRL YRIPQINMNK EAPRIRLIIS DALASAVSLQ NSLIGLPKGK 240
FSTDDEEATS KFIQARAIRR KVLRYLQLVT EGEFLGSLIH ANDELVAALT AYDDRSAQDD 300
SSDESDHGSY DDGIYDENEQ DNSRYIDSES SEEESLSSYQ PSTISNPFGD HNKI 354 
Gene Ontology
 GO:0030479; C:actin cortical patch; IDA:SGD.
 GO:0051666; P:actin cortical patch localization; IGI:SGD.
 GO:0007015; P:actin filament organization; IPI:SGD.
 GO:0006897; P:endocytosis; IGI:SGD.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR008942; ENTH_VHS.
 IPR004152; GAT. 
Pfam
 PF03127; GAT 
SMART
  
PROSITE
 PS50179; VHS 
PRINTS