CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007024
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TOM71 
Protein Synonyms/Alias
 71 kDa mitochondrial outer membrane protein 
Gene Name
 TOM71 
Gene Synonyms/Alias
 TOM72; YHR117W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
254VLNENLSKDEGRGSQubiquitination[1]
526GIGPLIGKATILARQubiquitination[1]
600LARTMDEKLQATTFAubiquitination[1]
611TTFAEAAKIQKRLRAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Involved in MBF1-mediated mitochondrial morphogenesis. 
Sequence Annotation
 REPEAT 127 160 TPR 1.
 REPEAT 162 194 TPR 2.
 REPEAT 345 378 TPR 3.
 REPEAT 379 411 TPR 4.
 REPEAT 412 445 TPR 5.
 REPEAT 447 479 TPR 6.
 REPEAT 480 513 TPR 7.
 REPEAT 530 563 TPR 8.
 REPEAT 565 597 TPR 9.
 MOD_RES 55 55 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Reference proteome; Repeat; TPR repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MAENSLLRFI TKNKVAILAT VSAGTAAVGA YVYYQQIKQQ QQQQLKGTKD NRRQSEAFAG 60
QNEDEADLKD DGSVVSGSNK RKKKKNKRKR NNKAKSGEGF DYPSLPNGEP DIAQLKGLSP 120
SQRQAYAVQL KNRGNHFFTA KNFNEAIKYY QYAIELDPNE PVFYSNISAC YISTGDLEKV 180
IEFTTKALEI KPDHSKALLR RASANESLGN FTDAMFDLSV LSLNGDFDGA SIEPMLERNL 240
NKQAMKVLNE NLSKDEGRGS QVLPSNTSLA SFFGIFDSHL EVSSVNTSSN YDTAYALLSD 300
ALQRLYSATD EGYLVANDLL TKSTDMYHSL LSANTVDDPL RENAALALCY TGIFHFLKNN 360
LLDAQVLLQE SINLHPTPNS YIFLALTLAD KENSQEFFKF FQKAVDLNPE YPPTYYHRGQ 420
MYFILQDYKN AKEDFQKAQS LNPENVYPYI QLACLLYKQG KFTESEAFFN ETKLKFPTLP 480
EVPTFFAEIL TDRGDFDTAI KQYDIAKRLE EVQEKIHVGI GPLIGKATIL ARQSSQDPTQ 540
LDEEKFNAAI KLLTKACELD PRSEQAKIGL AQLKLQMEKI DEAIELFEDS AILARTMDEK 600
LQATTFAEAA KIQKRLRADP IISAKMELTL ARYRAKGML 639 
Gene Ontology
 GO:0031307; C:integral to mitochondrial outer membrane; IDA:SGD.
 GO:0008565; F:protein transporter activity; IDA:SGD.
 GO:0006626; P:protein targeting to mitochondrion; IGI:SGD. 
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1
 PF13181; TPR_8 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS