UniProt Accession

 SHLB2_HUMAN; Q9NR46; A6NC47; A8MPS4; Q8WY61; Q96JH9 

Genbank Protein ID

 AF257319; AB058751; AF258589; AL592211; AL592211; BC014635 

Genbank Nucleotide ID

 AAF81226.1; BAB47477.2; AAG23792.1; CAI12365.1; CAI12366.1; AAH14635.1 

Protein Name

 Endophilin-B2 

Protein Synonyms/Alias

 SH3 domain-containing GRB2-like protein B2 

Gene Name

 SH3GLB2 

Gene Synonyms/Alias

 KIAA1848; PP578 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
26	AVQFTEEKFGQAEKT	ubiquitination	[1]
79	VEEFLYEKLDRKVPS	ubiquitination	[2]
123	IKVAEAEKQLGAAER	ubiquitination	[2]
153	NFLEGDWKTISKERR	ubiquitination	[2]
185	KAKAAEAKATTVPDF	ubiquitination	[2]
276	RHMLDLQKQLGRFPG	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 DOMAIN 24 287 BAR.
 DOMAIN 335 395 SH3.
 REGION 1 27 Membrane-binding amphipathic helix (By  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Polymorphism; Reference proteome; SH3 domain. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 395 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HGNC.
 GO:0005634; C:nucleus; IDA:HPA. 

Interpro

 IPR027267; AH/BAR-dom.
 IPR004148; BAR_dom.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 

Pfam

 PF03114; BAR
 PF07653; SH3_2 

SMART

 SM00721; BAR
 SM00326; SH3 

PROSITE

 PS51021; BAR
 PS50002; SH3 

PRINTS