CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025786
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Helicase and polymerase containing protein TEBICHI 
Protein Synonyms/Alias
 MUS308 and mammalian DNA polymerase-like protein 
Gene Name
 TEBICHI 
Gene Synonyms/Alias
 AT4G32700; At4g32700 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
449YPEPEGKKVLLCEENacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2154 AA 
Protein Sequence
MDSDSSKSRI DQFYVSKKRK HQSPNLKSGR NEKNVKVTGE RSPGDKGTLD SYLKASLDDK 60
STTNSGLQAR QEAFTRKLDL EVSASSVGQN IHPCLPKPVS FATFKECLGQ NGSQDLHKEG 120
VAAETHATDG LLCANQKDNS ELRDFATSFL SLYCSGVQSV VGSPPHQKEN ELKRRSSSSS 180
LAQDIQISHK RRCESENIPS LDDLTNPLGS KPESLARNGN NRDKPVSDPT KKMPSNESVE 240
IPMGLRKCSK APESSAHLTE FHTPGSAIKS CPVGTPKSGC GSSMFSPGEA FWNEAIQVAD 300
GLTIPIENFG SVEAKVRDQH VTILSCSKKT DKCTEKLERS LDLDEIRVKD KDAIGFSKVV 360
EKHGRDFNKE VYQLPVKNLE LLFQDKNING GIQERCASFD QNNITLGSSR ISESAFVGNK 420
GCENLDIANN AQADKGLIGK MYPEPEGKKV LLCEENRGVR SVSMISNMRK PVGSSESEES 480
HTPSSSHRNY DGLSLSTWLP SEVCSVYNKK GISKLYPWQV ECLQVDGVLQ KRNLVYCAST 540
SAGKSFVAEV LMLRRVIRTG KMALLVLPYV SICAEKAEHL EVLLEPLGKH VRSYYGNQGG 600
GTLPKDTSVA VCTIEKANSL INRLLEEGRL SELGIIVIDE LHMVGDQHRG YLLELMLTKL 660
RYAAGEGSSE SSSGESSGTS SGKADPAHGL QIVGMSATMP NVGAVADWLQ AALYQTEFRP 720
VPLEEYIKVG STIYNKKMEV VRTIPKAADM GGKDPDHIVE LCNEVVQEGN SVLIFCSSRK 780
GCESTARHIS KLIKNVPVNV DGENSEFMDI RSAIDALRRS PSGVDPVLEE TLPSGVAYHH 840
AGLTVEEREI VETCYRKGLV RVLTATSTLA AGVNLPARRV IFRQPMIGRD FIDGTRYKQM 900
SGRAGRTGID TKGDSVLICK PGELKRIMAL LNETCPPLQS CLSEDKNGMT HAILEVVAGG 960
IVQTAKDIHR YVRCTLLNST KPFQDVVKSA QDSLRWLCHR KFLEWNEETK LYTTTPLGRG 1020
SFGSSLCPEE SLIVLDDLLR AREGLVMASD LHLVYLVTPI NVGVEPNWEL YYERFMELSP 1080
LEQSVGNRVG VVEPFLMRMA HGATVRTLNR PQDVKKNLRG EYDSRHGSTS MKMLSDEQML 1140
RVCKRFFVAL ILSKLVQEAS VTEVCEAFKV ARGMVQALQE NAGRFSSMVS VFCERLGWHD 1200
LEGLVAKFQN RVSFGVRAEI VELTSIPYIK GSRARALYKA GLRTSQAIAE ASIPEIVKAL 1260
FESSAWAAEG TGQRRIHLGL AKKIKNGARK IVLEKAEEAR AAAFSAFKSL GLDVNELSKP 1320
LPLAPASSLN GQETTERDIS RGSVGPDGLQ QSIEGHMECE NFDMDNHREK PSEVLGDATL 1380
GVSSEINLTS RLPNFRPIGT AVGTNGPSAV SILSSDTFPI PVYDNREIKP KDNVEQHLTR 1440
NDHIPLSSNK DGTGEKGPVT AGNISGGFDS FLELWGSAGE FFFDLHYNKL QDLNSRISYE 1500
IHGIAICWNC SPVYYVNLNK DLPNLECVEK QKLIEDAVIG KSEVLASHNM LDVIKSRWNK 1560
ISKIMGNVNT RKFTWNLKVQ IQVLKSPAIS IQRCTRLNLP EGIRDELVDG SWLMMPPLHT 1620
SHTIDMSIVI WILWPDEERH SNPNIDKEVK KRLSPEAAEA ANRSGRWRNQ IRRVAHNGCC 1680
RRVAQTRALC SALWKILVSE ELLQALTTIE MPLVNVLADM ELWGIGIDIE GCLRARNILR 1740
DKLRSLEKKA FELAGMTFSL HNPADIANVL FGQLKLPIPE NQSKGKLHPS TDKHCLDLLR 1800
NEHPVVPIIK EHRTLAKLLN CTLGSICSLA KLRLSTQRYT LHGRWLQTST ATGRLSIEEP 1860
NLQSVEHEVE FKLDKNGRDV SSDADRYKIN ARDFFVPTQE NWLLLTADYS QIELRLMAHF 1920
SRDSSLISKL SQPEGDVFTM IAAKWTGKAE DSVSPHDRDQ TKRLIYGILY GMGANRLAEQ 1980
LECTSDEAKE KIRSFKSSFP AVTSWLNETI SFCQEKGYIQ TLKGRRRFLS KIKFGNAKEK 2040
SKAQRQAVNS MCQGSAADII KIAMINIYSA IAEDVDTAAS SSSSETRFHM LKGRCRILLQ 2100
VHDELVLEVD PSYVKLAAML LQTSMENAVS LLVPLHVKLK VGKTWGSLEP FQTD 2154 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0006310; P:DNA recombination; IGI:TAIR.
 GO:0006260; P:DNA replication; IGI:TAIR.
 GO:0009640; P:photomorphogenesis; IMP:TAIR.
 GO:0010468; P:regulation of gene expression; IGI:TAIR. 
Interpro
 IPR001098; DNA-dir_DNA_pol_A_palm_dom.
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR002298; DNA_polymerase_A.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00270; DEAD
 PF00476; DNA_pol_A
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc
 SM00482; POLAc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS
 PR00868; DNAPOLI.