CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008758
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphatidylinositol transfer protein beta isoform 
Protein Synonyms/Alias
 PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta 
Gene Name
 Pitpnb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
5***MVLIKEFRVVLPacetylation[1]
5***MVLIKEFRVVLPubiquitination[2]
54PYENDGEKGQYTHKIubiquitination[2]
65THKIYHLKSKVPAFVacetylation[1]
86GSLVFHEKAWNAYPYubiquitination[2]
194CPRMCAYKLVTIKFKacetylation[1]
199AYKLVTIKFKWWGLQacetylation[1]
201KLVTIKFKWWGLQSKacetylation[1]
201KLVTIKFKWWGLQSKubiquitination[2]
215KVENFIQKQEKRIFTacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes. 
Sequence Annotation
 MOD_RES 215 215 N6-acetyllysine (By similarity).
 MOD_RES 262 262 Phosphoserine; by PKC.  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Golgi apparatus; Lipid-binding; Phosphoprotein; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 271 AA 
Protein Sequence
MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEN DGEKGQYTHK 60
IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN EYMKDDFFIK IETWHKPDLG 120
TLENVHGLDP NTWKTVEIVH IDIADRSQVE PADYKADEDP ALFHSVKTKR GPLGPNWKKE 180
LANTPDCPRM CAYKLVTIKF KWWGLQSKVE NFIQKQEKRI FTNLHRQLFC WIDKWIDLTM 240
EDIRRMEDET QKELETMRKK GSVRGTSAAD A 271 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005543; F:phospholipid binding; ISA:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 
Pfam
 PF02121; IP_trans 
SMART
  
PROSITE
  
PRINTS
 PR00391; PITRANSFER.