UniProt Accession

 C9JSZ2_HUMAN; C9JSZ2 

Genbank Protein ID

 AC002094; AC015917 

Genbank Nucleotide ID

  

Protein Name

 Proton-coupled folate transporter 

Protein Synonyms/Alias

  

Gene Name

 SLC46A1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
262	YVAPAPEKSRKHLAL	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 430 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 

Interpro

 IPR011701; MFS.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005829; Sugar_transporter_CS. 

Pfam

 PF07690; MFS_1 

SMART

  

PROSITE

 PS00216; SUGAR_TRANSPORT_1 

PRINTS