CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043798
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Centrosome-associated protein CEP250 
Protein Synonyms/Alias
  
Gene Name
 CEP250 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62HKMECQQKLIKELEGubiquitination[1, 2]
65ECQQKLIKELEGQREubiquitination[1, 2, 3]
167DQRTRQTKILEEDLEubiquitination[1]
551EREQLLEKSLAQRVQubiquitination[1]
753PSPDGMEKQSWRQRLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 877 AA 
Protein Sequence
LEKDRETQRN VLEHQLLELE KKDQMIESQR GQVQDLKKQL VTLECLALEL EENHHKMECQ 60
QKLIKELEGQ RETQRVALTH LTLDLEERSQ ELQAQSSQIH DLESHSTVLA RELQERDQEV 120
KSQREQIEEL QRQKEHLTQD LERRDQELML QKERIQVLED QRTRQTKILE EDLEQIKLSL 180
RERGRELTTQ RQLMQERAEE GKGPSKAQRG SLEHMKLILR DKEKEVECQQ EHIHELQELK 240
DQLEQQLQGL HRKVGETSLL LSQREQEIVV LQQQLQEARE QGELKEQSLQ SQLDEAQRAL 300
AQRDQELEAL QQEQQQAQGQ EERVKEKADA LQGALEQAHM TLKERHGELQ DHKEQARRLE 360
EELAVEGRRV QALEEVLGDL RAESREQEKA LLALQQQCAE QAQEHEVETR ALQDSWLQAQ 420
AVLKERDQEL EALRAESQSS RHQEEAARAR AEALQEALGK AHAALQGKEQ HLLEQAELSR 480
SLEASTATLQ ASLDACQAHS RQLEEALRIQ EGEIQDQDLR YQEDVQQLQQ ALAQRDEELR 540
HQQEREQLLE KSLAQRVQEN MIQEKQNLGQ EREEEEIRGL HQSVRELQLT LAQKEQEILE 600
LRETQQRNNL EALPHSHKTS PMEEQSLKLD SLEPRLQREL ERLQAALRQT EAREIEWREK 660
AQDLALSLAQ TKASVSSLQE VAMFLQASVL ERDSEQQRLQ DELELTRRAL EKERLHSPGA 720
TSTAELGSRG EQGVQLGEVS GVEAEPSPDG MEKQSWRQRL EHLQQAVARL EIDRSRLQRH 780
NVQLRSTLEQ VVLLQAQLTL ERKQKQDYIT RSAQTSRELA GLHHSLSHSL LAVAQAPEAT 840
VLEAETRRLD ESLTQSLTSP GPVLLHPSPS TTQAASR 877 
Gene Ontology
 GO:0005814; C:centriole; IEA:InterPro. 
Interpro
 IPR026048; CEP250. 
Pfam
  
SMART
  
PROSITE
  
PRINTS