UniProt Accession

 DJB12_HUMAN; Q9NXW2; B7Z7I3; Q9H6H0 

Genbank Protein ID

 AK000034; AK025942; AK302071; AC091769; BC011812; BC064920 

Genbank Nucleotide ID

 BAA90896.1; BAB15289.1; BAH13619.1; AAH11812.2; AAH64920.1 

Protein Name

 DnaJ homolog subfamily B member 12 

Protein Synonyms/Alias

  

Gene Name

 DNAJB12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	RALRFLEKAQRLYPT	ubiquitination	[1]
73	TTHATHRKAGGTDAP	ubiquitination	[1, 2]
92	EAGGESTKGYTAEQV	ubiquitination	[1]
103	AEQVAAVKRVKQCKD	ubiquitination	[1]
109	VKRVKQCKDYYEILG	ubiquitination	[1, 3]
141	ALKFHPDKNHAPGAT	ubiquitination	[1, 3]
166	AVLSNPEKRKQYDQF	ubiquitination	[1, 3]
168	LSNPEKRKQYDQFGD	ubiquitination	[1]
177	YDQFGDDKSQAARHG	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

 DOMAIN 112 176 J.  

Keyword

 3D-structure; Alternative splicing; Chaperone; Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 375 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS.
 IPR015399; DUF1977_DnaJ-like. 

Pfam

 PF00226; DnaJ
 PF09320; DUF1977 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2 

PRINTS

 PR00625; JDOMAIN.