UniProt Accession

 GBG7_RAT; P43425; Q45QK4 

Genbank Protein ID

 L23219; DQ120497; DQ120498 

Genbank Nucleotide ID

 AAA65640.1; AAZ23836.1; AAZ23837.1 

Protein Name

 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 

Protein Synonyms/Alias

  

Gene Name

 Gng7 

Gene Synonyms/Alias

 Gngt7 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
60	PASENPFKDKKPCII	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 65 65 Cysteine methyl ester (By similarity).
 LIPID 65 65 S-geranylgeranyl cysteine (By  

Keyword

 Acetylation; Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 68 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; NAS:RGD.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0001662; P:behavioral fear response; IEA:Compara.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0007626; P:locomotory behavior; IEA:Compara.
 GO:0007168; P:receptor guanylyl cyclase signaling pathway; IEA:Compara.
 GO:0045761; P:regulation of adenylate cyclase activity; IEA:Compara. 

Interpro

 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 

Pfam

 PF00631; G-gamma 

SMART

 SM00224; GGL 

PROSITE

 PS50058; G_PROTEIN_GAMMA 

PRINTS

 PR00321; GPROTEING.