Tag | Content |
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CPLM ID | CPLM-014531 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tropomyosin alpha-3 chain |
Protein Synonyms/Alias | Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5 |
Gene Name | Tpm3 |
Gene Synonyms/Alias | Tpm-5; Tpm5 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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228 | EDELYAQKLKYKAIS | ubiquitination | [1] |
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Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
Sequence Annotation | MOD_RES 2 2 N-acetylalanine. |
Keyword | Acetylation; Actin-binding; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Muscle protein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 248 AA |
Protein Sequence | MAGSTTIEAV KRKIQVLQQQ ADDAEERAER LQREVEGERR AREQAEAEVA SLNRRIQLVE 60 EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRALK DEEKMELQEI QLKEAKHIAE 120 EADRKYEEVA RKLVIIEGDL ERTEERAELA ESKCSELEEE LKNVTNNLKS LEAQAEKYSQ 180 KEDKYEEEIK ILTDKLKEAE TRAEFAERSV AKLEKTIDDL EDELYAQKLK YKAISDELDH 240 ALNDMTSI 248 |
Gene Ontology | |
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PRINTS | |