CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002117
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Esterase FrsA 
Protein Synonyms/Alias
  
Gene Name
 frsA 
Gene Synonyms/Alias
 yafA; b0239; JW0229 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
12NLSETLFKPRFKHPEacetylation[1]
42VQSALDGKTIPHWYRacetylation[1]
141IAAYPHLKGDDLAEQacetylation[1]
240VGFSSKWKLTQDSSLacetylation[1]
254LLHQHVLKALPNVPWacetylation[1]
345ELNRYSLKVQGLLGRacetylation[1]
364PMLSGYWKNDPFSPEacetylation[1]
385TSSSADGKLLEIPFNacetylation[1]
400PVYRNFDKGLQEITDacetylation[1]
411EITDWIEKRLC****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Displays esterase activity toward pNP-butyrate. 
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome; Serine esterase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MTQANLSETL FKPRFKHPET STLVRRFNHG AQPPVQSALD GKTIPHWYRM INRLMWIWRG 60
IDPREILDVQ ARIVMSDAER TDDDLYDTVI GYRGGNWIYE WATQAMVWQQ KACAEDDPQL 120
SGRHWLHAAT LYNIAAYPHL KGDDLAEQAQ ALSNRAYEEA AQRLPGTMRQ MEFTVPGGAP 180
ITGFLHMPKG DGPFPTVLMC GGLDAMQTDY YSLYERYFAP RGIAMLTIDM PSVGFSSKWK 240
LTQDSSLLHQ HVLKALPNVP WVDHTRVAAF GFRFGANVAV RLAYLESPRL KAVACLGPVV 300
HTLLSDFKCQ QQVPEMYLDV LASRLGMHDA SDEALRVELN RYSLKVQGLL GRRCPTPMLS 360
GYWKNDPFSP EEDSRLITSS SADGKLLEIP FNPVYRNFDK GLQEITDWIE KRLC 414 
Gene Ontology
 GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.
 GO:0031670; P:cellular response to nutrient; IMP:EcoCyc.
 GO:0006113; P:fermentation; EXP:EcoCyc. 
Interpro
 IPR010520; DUF1100_hydro-like. 
Pfam
 PF06500; DUF1100 
SMART
  
PROSITE
  
PRINTS