UniProt Accession

 CHZ1_YEAST; P40019; D3DLS9 

Genbank Protein ID

 U18778; BK006939 

Genbank Nucleotide ID

 AAB64563.1; DAA07683.1 

Protein Name

 Histone H2A.Z-specific chaperone CHZ1 

Protein Synonyms/Alias

  

Gene Name

 CHZ1 

Gene Synonyms/Alias

 YER030W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
47	DYDAEVAKEETKAKN	acetylation	[1]
51	EVAKEETKAKNGLTK	acetylation	[1]
123	KTAEELDKKEPSTGS	acetylation	[1]
131	KEPSTGSKDDVGYGE	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin. 

Sequence Annotation

 REGION 87 108 Important for H2A.Z-H2B binding.
 MOD_RES 68 68 Phosphoserine.
 MOD_RES 70 70 Phosphoserine.  

Keyword

 3D-structure; Chaperone; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 153 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:SGD.
 GO:0006338; P:chromatin remodeling; IPI:SGD. 

Interpro

 IPR019098; Histone_chaperone_domain_CHZ. 

Pfam

 PF09649; CHZ 

SMART

 SM01082; CHZ 

PROSITE

  

PRINTS