CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021352
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pancreatic progenitor cell differentiation and proliferation factor 
Protein Synonyms/Alias
 Exocrine differentiation and proliferation factor 
Gene Name
 PPDPF 
Gene Synonyms/Alias
 C20orf149; EXPDF 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
99LARDAPRKQPGGQSSubiquitination[1, 2, 3, 4, 5, 6]
Reference
 [1] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [6] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
 Probable regulator of exocrine pancreas development (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Developmental protein; Differentiation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 114 AA 
Protein Sequence
MAAIPSSGSL VATHDYYRRR LGSTSSNSSC SSTECPGEAI PHPPGLPKAD PGHWWASFFF 60
GKSTLPFMAT VLESAEHSEP PQASSSMTAC GLARDAPRKQ PGGQSSTASA GPPS 114 
Gene Ontology
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. 
Interpro
 IPR026754; PPDPF. 
Pfam
  
SMART
  
PROSITE
  
PRINTS