CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033846
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex, 5, isoform CRA_a 
Protein Synonyms/Alias
 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 
Gene Name
 Ndufa5 
Gene Synonyms/Alias
 mCG_22853 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57SLARKMLKWKPWEPLacetylation[1]
59ARKMLKWKPWEPLVEacetylation[1, 2, 3, 4]
59ARKMLKWKPWEPLVEsuccinylation[4]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ubiquinone. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 77 AA 
Protein Sequence
MAGLLKKTTG LVGLAVCDTP HEEPDVKKLE ALLQGGEVEE VILQAEKELS LARKMLKWKP 60
WEPLVEEPPA NQWKWPI 77 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS