CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005121
UniProt Accession
Genbank Protein ID
 D00631 
Genbank Nucleotide ID
Protein Name
 Phenylalanine dehydrogenase 
Protein Synonyms/Alias
 PheDH 
Gene Name
 pdh 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Thermoactinomyces intermedius 
NCBI Taxa ID
 2024 
Lysine Modification
Position
Peptide
Type
References
69LSKGMTYKCSLADVDacetylation[1]
81DVDFGGGKMVIIGDPacetylation[1]
Reference
 [1] Identification of active site lysyl residues of phenylalanine dehydrogenase by chemical modification with methyl acetyl phosphate combined with site-directed mutagenesis.
 Kataoka K, Tanizawa K, Fukui T, Ueno H, Yoshimura T, Esaki N, Soda K.
 J Biochem. 1994 Dec;116(6):1370-6. [PMID: 7706231] 
Functional Description
  
Sequence Annotation
 NP_BIND 181 187 NAD (Potential).
 ACT_SITE 81 81 By similarity.  
Keyword
 Direct protein sequencing; NAD; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MRDVFEMMDR YGHEQVIFCR HPQTGLKAII ALHNTTAGPA LGGCRMIPYA STDEALEDVL 60
RLSKGMTYKC SLADVDFGGG KMVIIGDPKK DKSPELFRVI GRFVGGLNGR FYTGTDMGTN 120
PEDFVHAARE SKSFAGLPKS YGGKGDTSIP TALGVFHGMR ATARFLWGTD QLKGRVVAIQ 180
GVGKVGERLL QLLVEVGAYC KIADIDSVRC EQLKEKYGDK VQLVDVNRIH KESCDIFSPC 240
AKGGVVNDDT IDEFRCLAIV GSANNQLVED RHGALLQKRS ICYAPDYLVN AGGLIQVADE 300
LEGFHEERVL AKTEAIYDMV LDIFHRAKNE NITTCEAADR IVMERLKKLT DIRRILLEDP 360
RNSARR 366 
Gene Ontology
 GO:0050175; F:phenylalanine dehydrogenase activity; IEA:EC.
 GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR006095; Glu/Leu/Phe/Val_DH.
 IPR006096; Glu/Leu/Phe/Val_DH_C.
 IPR006097; Glu/Leu/Phe/Val_DH_dimer_dom.
 IPR016211; Glu/Phe/Leu/Val_DH_bac/arc.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF00208; ELFV_dehydrog
 PF02812; ELFV_dehydrog_N 
SMART
 SM00839; ELFV_dehydrog 
PROSITE
 PS00074; GLFV_DEHYDROGENASE 
PRINTS
 PR00082; GLFDHDRGNASE.