UniProt Accession

 D3YY95_MOUSE; D3YY95 

Genbank Protein ID

 AC154523 

Genbank Nucleotide ID

  

Protein Name

 Alpha-actinin-2 

Protein Synonyms/Alias

  

Gene Name

 Actn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
54	WCNSHLRKAGTQIEN	ubiquitination	[1]
102	HKIANVNKALDYIAS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Actin-binding; Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 159 AA 

Protein Sequence

Gene Ontology

 GO:0005865; C:striated muscle thin filament; TAS:MGI.
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0051015; F:actin filament binding; IDA:MGI.
 GO:0030674; F:protein binding, bridging; TAS:MGI.
 GO:0030375; F:thyroid hormone receptor coactivator activity; IDA:MGI.
 GO:0051764; P:actin crosslink formation; IEA:InterPro.
 GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
 GO:0006936; P:muscle contraction; IDA:MGI. 

Interpro

 IPR001589; Actinin_actin-bd_CS.
 IPR026921; Alpha-actinin.
 IPR001715; CH-domain. 

Pfam

 PF00307; CH 

SMART

 SM00033; CH 

PROSITE

 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH 

PRINTS