UniProt Accession

 AB17C_HUMAN; Q6PCB6; Q1RMD6; Q9NPM1 

Genbank Protein ID

 BC059401; BC115003; AL390079 

Genbank Nucleotide ID

 AAH59401.2; AAI15004.1; CAB98203.1 

Protein Name

 Alpha/beta hydrolase domain-containing protein 17C 

Protein Synonyms/Alias

  

Gene Name

 ABHD17C 

Gene Synonyms/Alias

 FAM108C1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
32	CPSRIAAKLAFLPPE	ubiquitination	[1, 2, 3]
177	GYGVSSGKPSEKNLY	ubiquitination	[2, 3]
263	PSIDKISKVTSPVLV	ubiquitination	[3]
319	AQYLERLKQFISHEL	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 ACT_SITE 211 211 Charge relay system (By similarity).
 ACT_SITE 276 276 Charge relay system (By similarity).
 ACT_SITE 305 305 Charge relay system (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 329 AA 

Protein Sequence

Gene Ontology

 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS