CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Flotillin-1 
Protein Synonyms/Alias
  
Gene Name
 FLOT1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
61ERLAEAEKSQLIMQAubiquitination[1]
181SISQVNHKPLRTA**ubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
VAKTKQQIEE QRVQVQVVER AQQVAVQEQE IARREKELEA RVRKPAEAER YKLERLAEAE 60
KSQLIMQAEA EAASVRMRGE AEAFAIGARA RAEAEQMAKK AEAFQLYQEA AQLDMLLEKL 120
PQVAEEISGP LTSANKITLV SSGSGTMGAA KVTGEVLDIL TRLPESVERL TGVSISQVNH 180
KPLRTA 186 
Gene Ontology
 GO:0016600; C:flotillin complex; IEA:Compara.
 GO:0042383; C:sarcolemma; IEA:Compara.
 GO:0007409; P:axonogenesis; IEA:Compara.
 GO:0072659; P:protein localization to plasma membrane; IEA:Compara.
 GO:0035023; P:regulation of Rho protein signal transduction; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS