CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025357
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 X-prolyl aminopeptidase (Aminopeptidase P) 1, soluble, isoform CRA_b 
Protein Synonyms/Alias
  
Gene Name
 Xpnpep1 
Gene Synonyms/Alias
 mCG_20868 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
484GTPTAYEKECFTYVLubiquitination[1]
589VVLVVPAKTKYNFNNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminopeptidase; Hydrolase; Metal-binding; Protease. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 666 AA 
Protein Sequence
MAASRKPPRV RANRQDFQLR NLRIIEPNEV TPSGDKSVET DHRMAPKVTS ELLRQLRQAM 60
RNSEYVAEPI QAYIIPSGDA HQSEYIAPCD CRRAFVSGFD GSAGTAIITE EHAAMWTDGR 120
YFLQAAKQMD NNWTLMKMGL KDTPTQEDWL VSVLPEGSRV GVDPLIIPTD YWKKMAKVLR 180
SAGHHLVPVK ENLVDKIWTD RPERPCKPLL TLGLDYTGIS WKEKVADLRL KMAERSIAWF 240
VVTALDEIAW LFNLRGSDVE HNPVFFSYAI VGLETIMLFI DGDRVDAPGV KQHLLLDLGL 300
EAEYRIQVLP YKSILSELKA LCADLSPREK VWVSDKASYA VSEAIPKDHR CCMPYTPICI 360
AKAVKNSAES DGMRRAHIKD AVALCELFNW LEQEVPKGGV TEISAADKAE EFRRQQADFV 420
DLSFPTISST GPNGAIIHYA PVPETNRTLS LDEVYLIDSG AQYKDGTTDV TRTMHFGTPT 480
AYEKECFTYV LKGHIAVSAA VFPTGTKGHL LDSFARSALW DSGLDYLHGT GHGVGSFLNV 540
HEGPCGISYK TFSDEPLEAG MIVTDEPGYY EDGAFGIRIE NVVLVVPAKT KYNFNNRGSL 600
TFEPLTLVPI QTKMIDVNAL TDKECDWLNS YHQTCRDVVG KELQSQGRQE ALEWLIRETE 660
PVSRQH 666 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0030145; F:manganese ion binding; IEA:Compara.
 GO:0070006; F:metalloaminopeptidase activity; IEA:Compara.
 GO:0010815; P:bradykinin catabolic process; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:Compara. 
Interpro
 IPR000587; Creatinase.
 IPR000994; Pept_M24_structural-domain.
 IPR001131; Peptidase_M24B_aminopep-P_CS. 
Pfam
 PF01321; Creatinase_N
 PF00557; Peptidase_M24 
SMART
  
PROSITE
 PS00491; PROLINE_PEPTIDASE 
PRINTS