UniProt Accession

 TPD52_HUMAN; P55327; B7Z414; E5RKB4; Q13056; Q53EK8; Q6FGP3; Q6FGS3; Q86YZ2; Q9UCX8 

Genbank Protein ID

 U18914; S82081; AF202897; AK295468; AK296615; AK313135; CR542034; CR542064; BT019444; BX640835; AK223631; AC009686; AC018952; AC036214; AC104212; CH471068; BC018117 

Genbank Nucleotide ID

 AAC50183.1; AAB36475.1; AAO22156.1; BAH12078.1; BAH12400.1; BAG35954.1; CAG46831.1; CAG46861.1; AAV38251.1; CAE45908.1; BAD97351.1; EAW87074.1; AAH18117.1 

Protein Name

 Tumor protein D52 

Protein Synonyms/Alias

 Protein N8 

Gene Name

 TPD52 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
124	LSQVLAAKEKHLAEI	ubiquitination	[1]
149	ELKQNIAKGWQDVTA	ubiquitination	[1, 2]
161	VTATSAYKKTSETLS	ubiquitination	[1]
162	TATSAYKKTSETLSQ	ubiquitination	[2]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

 MOD_RES 171 171 Phosphoserine.
 MOD_RES 173 173 Phosphothreonine.
 MOD_RES 176 176 Phosphoserine.
 MOD_RES 223 223 Phosphoserine.  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 224 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
 GO:0005509; F:calcium ion binding; IDA:UniProtKB.
 GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
 GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
 GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
 GO:0030183; P:B cell differentiation; IEP:UniProtKB.
 GO:0046903; P:secretion; TAS:UniProtKB. 

Interpro

 IPR007327; TPD52. 

Pfam

 PF04201; TPD52 

SMART

  

PROSITE

  

PRINTS