CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034144
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dnah10 
Protein Synonyms/Alias
  
Gene Name
 Dnah10 
Gene Synonyms/Alias
 Dnahc10 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1517VKEVAIEKAVKEILDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 4591 AA 
Protein Sequence
MDDLRVLWMR DRVYTAFNLT NPMLFEEMLS RDDSEAEDCI LHFLNHLSDE DNASALFFYR 60
ILVPEEVEVE EPDIPLVFDE EGEEEESDYQ KVEATEKMSV KFSKLRSDSM TPSLFDMDDE 120
EPDVETYSKL YGKKIVKRII NKLELRVNLA SLPEEFLQQN VVFFLRSSKD AIPEATDMKE 180
AMEIMPETME YGVINSQVLQ LLKDVICQVF MPALSFNQHK SESGQGTLSG ENQEFSVYDL 240
AESVVIPGEP MEYHSVQLIR DEFLMNLQKF ENNIQRTIQQ LEGEIKLEMP SISVEGDMSE 300
LVSNPELVEN LEQCVIHWLG QISYALDSQM KKKPQGNGPL AEIEFWRERN ATLSALYEQT 360
KLPFVRKVLE VIKEAESMLT ANVQPILTEL FKLHMEASDN VRFLSTVERH FKNITHGSSF 420
HVVLDTIPSM MSALRMVWII SRHYNRDERM IPLMERIAWE IAERVCRVIN LRTLFKENRA 480
NAQFKTQEAR NTLKLWKKSY FDIRAKIEAS GREARWEFDR KRLFERTDYM ANICQDLSDV 540
LQVLEEFYNI FGPELKAVTG DPKRIDDVLG RVDSLVAPME SLSFDPFSIR SSPYWKYVME 600
DFKLEVLVIE KEAKNFIDES FKTLRSAEAA FDMLLKFKHI RSREAINRQM MMKFNDILAQ 660
YYKEIDIVNK IFVQNQDNPP LYKNHPPVAG AICWERSLFY RIKHTILRFM EVEELLDSER 720
GQQVKQRYLE VGRKMKEYED GKYEHWKETT EQSLPTLMKK SLLTKNIITA EDSAIIDRGT 780
TFIINFSPVL KEIINETKYL EQLGFTIPEL ARNVALQEDK FLRYTEGIQR MLDHYHLLIN 840
TLNEAETALL DDHSQELLRV FRSGYKRLNW NSLGISDYIT RCKQAIGKFE TLVHQIHKNA 900
DDINSRLTLI ESVSLFRFPV AKTADGVPGV KEFFEYIERE RARDVDHMVR WYMAIGPLLT 960
KVEGLVVHTN TGRAPKLASY YEYWEGKIYD VLVKLIQKNL QAFNSLILRN VPLFQAETIL 1020
SAPEIVLHPN ANEIDKMCVH CVRSCVEVTK HFVRWMNGSC IECPPQKGEE EEVVIISFYN 1080
DISQNTQIMD QALMIPQNIH RLLVNIMKYL QRWKRYRPLW KLDKSIVMEK FAAKKPACVA 1140
YDEKLQFYSK IATDVMRHPL IKDEHCIRLQ LEPLASTVQE NAKSWVISLG KLLNESAREE 1200
LYSLRDEIEH LAKNLKKSPS TLEDLKFVLA TISEIRSKSL VMELRYKDIQ ERYRTMAIYK 1260
IFPTDTEQEL VNNIENMWES LFTESMNVEH ALGGIKRTFT EITRSEIMNY RSQLDEFARR 1320
FYSQGPGAVG EDLDKGSELL GSFEKELAKH EKNRQELANA EKLFDLPITM YPELIKVQKE 1380
MTGLRMIYEL YNSLKLAKEE WSQTLWINLN VQYLQEGIEG FLKNLRKLPR QVRGLSVAFH 1440
LEVKMKAFKD SIPLLLDLKH EALRERHWKE LMEKTGVFFE MTETFTLENM FAMELHKHTE 1500
VLNEIVTAAV KEVAIEKAVK EILDTWENMK FTVVKYYKGT QERGYILGSV DDIIQCLDDN 1560
TVNLQSISGS RFVGPFLQTV HKWEKTLSLI GEVIEIWMLV QRKWMYLESI FIGGDIRSQL 1620
PEEAKKFDNI DRIFKRIMGE TLKDPVIKRC CEAPNRLHDL QTISEGLEKC QKSLNDYLDS 1680
KRNAFPRFFF ISDDELLSIL GNSDPLCVQE HMIKMYDNIA MLRFHDGDSG EKLVSAMISA 1740
EGEVMTFRKI IRADGRVEDW MTAVLHEMRR TNRLITKEAI FRYCEDRSRV DWMLLYQGMV 1800
VLAASQVWWT WEVEDVFNKV KQGDKQAMKN YGKKMHSQID DLVTRITMEL SKNDRKKYNT 1860
VLIIDVHARD IVDSFIRGSI LEAREFEWES QLRFYWDREP DELNIRQCTG TFSYGYEYMG 1920
LNGRLVITPL TDRIYLTLTQ ALSMYLGGAP AGPAGTGKTE TTKDLAKALG LLCVVTNCGE 1980
GMDYKAVGKI FSGLAQCGAW GCFDEFNRID ASVLSVISSQ IQTIRNALIH QLTTFQFEGQ 2040
EISLDSRMGI FITMNPGYAG RTELPESVKA LFRPVVVIVP DLQQICEIML FSEGFLGAKT 2100
LAKKMTVLYK LAREQLSKQH HYDFGLRALK SVLVMAGELK RGSADLQEDV VLMRALRDMN 2160
LPKFVFEDVP LFLGLISDLF PGLDCPRVRY PDFNDAVEQV LEENGYVLLP VQVDKVVQMF 2220
ETMLTRHTTM VVGPTGGGKS VVINTLCQAQ TKLGIMTKLY ILNPKAVSVI ELYGILDPTT 2280
RDWTDGVLSN IFREINRPTD KKERKYILFD GDVDALWVEN MNSVMDDNKL LTLANGERIR 2340
LQAHCALLFE VGDLQYASPA TVSRCGMVYV DPKNLKYQPY WKKWLQQIQN KVEQKYLNDL 2400
FEKYVPTLID MIIEGIVDGR QGEKLKMVVP QTDLNMVTQL TRMLDSLLEG EIEDLDLLEC 2460
FFLEALYCSL GSSLLEEGRV KFDECIKRLS SMPTVDSEGN WARPGELPGH LPSLYDFHFD 2520
AKRNHWIPWN KLVPEYVHSH EKKFVDILVH TVDTTRTTWI LEQMVKIKHP VLFVGESGTS 2580
KTATTQNFLK NLNEETNIVL IVNFSSRTTS LDIQRNLEAN VEKRTKDTYG PPMGKRLLVF 2640
MDDMNMPKVD EYGTQQPIAL LKLLLEKGYL YDRGKELNCK SIRDLGFIAA MGKAGGGRNE 2700
VDPRFLSLFS VFNVPFPSEE SLNLIYYSIL KGHTSTFNES IGGVSRKLTF CTLTLYKNIV 2760
QDLPPTPSKF HYIFNLRDLS RVFNGLVLTN PDRFQTVSQM VRVWRNECLR VFHDRLINEV 2820
DKELVQNHIG NLVTEHFNDD FEMVMRDPIL FGDFRLALQE GEPRIYEDIQ DYEAAKALFE 2880
EILEEYNEVN TKMNLVLFDD ALEHLTRVHR IIRMDRGHAL LVGVGGSGKQ SLARLAAFTA 2940
GCEVFEILLS RGYSENNFRD DLKNLYMKLG LENKMMIFLF TDAHVAEEGF LELINNMLTS 3000
GMVPALFAEE EKDNILGQIG QEALKFGMGP AKESVWQFFV NKSANNLHIV LGMSPVGDTL 3060
RTRCRNFPGL VNNTGIDWFM PWPPQALHAV AKSFLGDNSM IPDEKLEELV EHVVMVHQSV 3120
GEFSKQFQQK LRRSNYVTPK NYLDFINTYS KLLDEKTQYN IAQCKRLEGG LDKLKEATIQ 3180
LDELNLKLAE QKIVLAEKSA ACEALLEEIA TNTAIAEEKK KLAEEKAIEI EEQNKIIAVE 3240
KAEAETALAE VMPILEAAKL ELQKLDKSDV TEIRSFAKPP KQVQTVCECI LIMKGYKELN 3300
WKTAKGMMSD PNFLRSLMEI DFDSITQGQV KNIKGLLKTL NTTIEEMEAV SKAGLGMLKF 3360
VEAVMGYCDV FREIKPKREK VARLERNFFL TKRELERIQN ELAAIQKELE ALGAKYEAAI 3420
LEKQKLQEEA EIMERRLIAA DKLISGLGSE NVRWLNDLDE LMHRRVKLLG DCLLCAAFLS 3480
YEGAFTWEFR DEMVNQVWQN DILDRDIPLS QPFRLENLLT DDVEISRWGS QGLPPDELSV 3540
QNGILTTRAS RFPLCIDPQQ QALNWIKRKE EKNNLRVASF NDPDFLKQLE MSIKYGTPFL 3600
FHDVDEYIDP VIDSVLEKNI KTSQGRQFII LGDKEVDYDS NFRLYLNTKL ANPRYSPSVF 3660
GKAMVINYTV TLKGLEDQLL SVLVAYERRE LEEQREHLIQ ETSENKNLLK DLEDSLLREL 3720
ATSTGNMLDN VELVQTLEET KSKATEVSEK LKLAEKTALD IDRLRDGYRP AARRGAILFF 3780
VLSEMALVNS MYQYSLIAFL EVFGLSLKKS LPDSILLKRL KNIMDTLTFN IYNYGCTGLF 3840
ERHKLLFSFN MTIKIEQAEG RVPQEELDFF LKGNISLEKS KWKKPCTWLS DQGWEDIILL 3900
SQKFSDIFGN LPLDIEHHLP MWQEWYDQDS LEQFPFPLGY DDNITAFQKL LILRCFRVDR 3960
VYRAVTDYVT LTMGEKYVQP PMISFEAIFE QSTPNSPIVF ILSPGSDPAS DLMKLAERSG 4020
FGGTRLKFLA MGQGQEKVAL QLLETAVARG QWLMLQNCHL LVKWLKDLEK SLERITKPHP 4080
DFRLWLTTDP TKGFPIGILQ KSLKVVTEPP NGLKLNMRAT YFKISNDMLE QCPHTAFKPL 4140
VYVLAFFHAV VQERRKFGKI GWNVYYDFNE SDFQVCMEIL NTYLTKAFQQ RDPRIPWGSL 4200
KYLIGEVMYG GRAIDSFDRR ILTTYMDEYL GDFIFDTFQP FHFFRNKDVD YKIPVGDIKD 4260
KFVEAIEALP LANTPEVFGL HSNAEIGYYT QAARDMWGHL LELQPQTGES SSGVSRDDYI 4320
GQVAKDIENK MPKIFDLDQV RKHLGLSITP TSVVLLQELG RFNKLVIRMT RSLAELQRAL 4380
AGEVGMSNEL DDVARSLFLG HIPHIWRKLA PDTLKTLGNW MVYFLRRFSQ YTLWVTEGEP 4440
SVMWLSGLHI PESYLTALVQ ATCRRNGWPL DRSTLFTQVT KFQDADEVNE RAGQGCFVSG 4500
LYLEGADWDI ERGCLVKSKP KVLVVDLPIL KIIPTEGHRL KLQNTFRTPV YTTSMRRNAM 4560
GIGLVFEADL FTAKHISHWV LQGVCLTLNS D 4591 
Gene Ontology
 GO:0005858; C:axonemal dynein complex; TAS:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0003777; F:microtubule motor activity; TAS:MGI.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0007018; P:microtubule-based movement; TAS:MGI. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR011704; ATPase_dyneun-rel_AAA.
 IPR026983; DHC_fam.
 IPR024743; Dynein_HC_stalk.
 IPR024317; Dynein_heavy_chain_D4_dom.
 IPR004273; Dynein_heavy_dom.
 IPR013594; Dynein_heavy_dom-1.
 IPR013602; Dynein_heavy_dom-2.
 IPR027417; P-loop_NTPase. 
Pfam
 PF07728; AAA_5
 PF12780; AAA_8
 PF08385; DHC_N1
 PF08393; DHC_N2
 PF03028; Dynein_heavy
 PF12777; MT 
SMART
 SM00382; AAA 
PROSITE
  
PRINTS