CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021050
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxisomal acyl-coenzyme A oxidase 3 
Protein Synonyms/Alias
 Branched-chain acyl-CoA oxidase; BRCACox; Pristanoyl-CoA oxidase 
Gene Name
 Acox3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
49QDVIHFKKTIFSTLEubiquitination[1]
73GADLPLEKLRELNFLubiquitination[1]
250MVGDIGKKLGQNGLDubiquitination[1]
291GTYNSPFKDVRQRLGubiquitination[1]
408HALASAGKPLASWTAubiquitination[1]
499YPGILGQKFLGSSKAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity). 
Sequence Annotation
 MOTIF 698 700 Microbody targeting signal (By
 MOD_RES 281 281 Phosphothreonine (By similarity).  
Keyword
 Complete proteome; FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Oxidoreductase; Peroxisome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 700 AA 
Protein Sequence
MGSLPEEKDS ALWSDTPKGP LSAYRARASF NSGELLLFWD GQDVIHFKKT IFSTLENDPL 60
FARSYGADLP LEKLRELNFL RCKRVFEYGF FKVEELLKNP LKILVLINCL GMYDWSLANK 120
CVLHMLVFGT TVFVSGSEKH FKYLEKIYSL EIFGCFALTE LSHGSNTKAM RTTAHYDPDT 180
QEFILHSPDF EAAKFWVGNL GKTATHAVVF AQLYMPDGQC HGLHSFLVQI RDTKTLLPMT 240
GVMVGDIGKK LGQNGLDNGF AMFNKVRIPR QNLLDRTGNI TSEGTYNSPF KDVRQRLGAS 300
LGSLSSGRIS IISMSVVNLK LAVSIAIRFS ATRCQFGPTD KEEIPVLEYP LQQWRILPYL 360
AAAYALDHFS KTIFMDLIEV QSARLRGDHS DQQAELGREI HALASAGKPL ASWTAQRGIQ 420
ECREACGGHG YLAMNRFGDL RNDNDPNCTY EGDNNVLLQQ TSNYLLSLLE PPLQDGAHFT 480
SPLKTVDFLE AYPGILGQKF LGSSKADWMD SAAPLAAYRW LVCYLLQESH RRYCQEKKSR 540
GSDFEARNNS QVYGCRPLAL AFMELTVMQR FHEHIHSSGL SPSLRTVLGR LSTLYGLWCL 600
SQHMALLYRG GYISGEQTGR AMEDAILTLC EQLKDDAVAL VDVIAPSDFV LNSPIAKADG 660
ELYKNLWAAV LQQNGVLERA AWWPEFSANK SVADRLKSQL 700 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005782; C:peroxisomal matrix; TAS:MGI.
 GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016402; F:pristanoyl-CoA oxidase activity; TAS:MGI.
 GO:0006635; P:fatty acid beta-oxidation; TAS:MGI.
 GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IEA:UniProtKB-UniPathway. 
Interpro
 IPR006090; Acyl-CoA_Oxase/DH_1.
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR012258; Acyl-CoA_oxidase.
 IPR002655; Acyl-CoA_oxidase_C.
 IPR009075; AcylCo_DH/oxidase_C.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF01756; ACOX
 PF00441; Acyl-CoA_dh_1
 PF02770; Acyl-CoA_dh_M 
SMART
  
PROSITE
  
PRINTS