CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022499
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 581 
Protein Synonyms/Alias
  
Gene Name
 ZNF581 
Gene Synonyms/Alias
 HSPC189 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
190MEQNTLQKHTRWKHPubiquitination[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 ZN_FING 87 109 C2H2-type 1.
 ZN_FING 115 137 C2H2-type 2.
 ZN_FING 145 167 C2H2-type 3.
 ZN_FING 173 196 C2H2-type 4.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 197 AA 
Protein Sequence
MLVLPSPCPQ PLAFSSVETM EGPPRRTCRS PEPGPSSSIG SPQASSPPRP NHYLLIDTQG 60
VPYTVLVDEE SQREPGASGA PGQKKCYSCP VCSRVFEYMS YLQRHSITHS EVKPFECDIC 120
GKAFKRASHL ARHHSIHLAG GGRPHGCPLC PRRFRDAGEL AQHSRVHSGE RPFQCPHCPR 180
RFMEQNTLQK HTRWKHP 197 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS