Tag | Content |
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CPLM ID | CPLM-044075 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zn finger homeodomain 2, isoform B |
Protein Synonyms/Alias | |
Gene Name | zfh2 |
Gene Synonyms/Alias | CG1449; Dmel_CG1449 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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1299 | SDGPVGIKQERLEQE | acetylation | [1] | 1837 | QKANLPMKVVKHWFR | acetylation | [1] | 2115 | KKMQIVGKTFEKNVA | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3003 AA |
Protein Sequence | MSSFDVETFN GKIVYNLDGS AHIIATDNTN GGGSGSGQNC YGSTTNSLKN LSKDKGRGQE 60 EKDIEHPSQY HREQSDNKRQ EEAVDNRPGV ESLGSACYKS SPKIHSFRVV SAQDANSTCQ 120 DQIRAFKIQK PILMCFICKL SFGNVKSFSL HANTEHRLNL EELDQQLLNR EYSSAIIQRN 180 MDEKPQISFL QPLANNDASA DTNDTEKLQT ATEGSDATLP SSPQPVFRNV SELEPENKQE 240 TEQNRLLNQD REQEPESDQH TSSSKMAAPS AYIPLSSPKV AGKLTVKFGS LNSATAKTNN 300 LSKVSSTSSP PSTYASGEVL SPSTDNISNH KSTHCNQETE PPSSSSSEVE MKIGSMSTSP 360 QTNDSDVPCS GFLQMQHMTT GGAYTPQVSS FHASLAALAA NESNDNRVKL ITEFLQQQLQ 420 QHQSSLFPSP CPDHPDLNGV DCKTCELLDI QQRSKSPSSS HHQFSQSLPQ LQIQSQPQQT 480 PHRSPCSNSV ALPVSPSASS VASVGNASTA TSSFTIGACS EHINGRPQGV DCARCEMLLN 540 SARLNSGVQM STRNSCKTLK CPQCNWHYKY QETLEIHMRE KHPDGESACG YCLAGQQHPR 600 LARGESYSCG YKPYRCEICN YSTTTKGNLS IHMQSDKHLN NMQELNSSQN MVAAAAAAAV 660 TGKLLLSSSS PQVTAACPSN SGSGAGSGSS NIVGGTASLS GNATPSVTGA NSSNANAGSN 720 TNNAGTKPKP SFRCDICSYD TSVARNLRIH MTSEKHTHNM AVLQNNIKHI QAFNFLQQQQ 780 QSGTGNIASH SSGSFMPEVA LADLAYNQAL MIQLLHQQQQ HQQSANTKLS PSSSPVSTPD 840 QFSFSPKPIK LNHGTGAAMG IGMAMGMGMS HSNEVSCELS GDPHPLTKTD KWPMAFYSCL 900 VCDCYSTNNL DDLNQHLLLD RSRQSSSASS EIMVIHNNNY ICRLCNYKTN LKANFQLHSK 960 TDKHLQKLNF INHIREGGPQ NEYKMQYQQQ QLAANVVQLK CNCCDFHTNS IQKLSLHTQQ 1020 MRHDTMRMIF QHLLYIVQQS EMHNKSSGSA EDDPQCACPD EDQQLQLQSS KKLLLCQLCN 1080 FTAQNIHEMV QHVKGIRHLQ VEQFICLQRR SENQEIPALN EVFKVTEWVM ENEDVSLAPG 1140 LNLARTTTND ATTDASYAAA SSAAVPAIPD VSMFSPTSPS SCATSCDKNL SQIVLPNVNN 1200 LGSGVPTTVF KCNLCEYFVQ SKSEIAAHIE TEHSCAESDE FITIPTNTAA LQAFQTAVAA 1260 AALAAVHQRC AVINPPTQDT VDEDKDLDTN VSDGPVGIKQ ERLEQEVDRT TSMDVTKDLA 1320 SQATDFGAPE SPKVAETEVG VQCPLCLENH FREKQYLEDH LTSVHSVTRD GLSRLLLLVD 1380 QKALKKESTD IACPTDKAPY ANTNALERAP TPIENTCNVS LIKSTSANPS QSVSLQGLSC 1440 QQCEASFKHE EQLLKHAQQN QHFSLQNGEY LCLAASHISR PCFMTFRTIP TMISHFQDLH 1500 MSLIISERHV YKYRCKQCSL AFKTQEKLTT HMLYHSMRDA TKCSFCQRNF RSTQALQKHM 1560 EQAHAEDGTP STRTNSPQTP MLSTEETHKH LLAESHAVER VSGSDVSPIE LETHLNKETR 1620 HLSPTPMSLD SQSHQKHLAT FAALLKQQQC NSDAGGLHPE ALSMSTGEMP PQLQGLQNLQ 1680 HIQQHFGAVA AAAGLPINPV DMLNIMQFHH LMSLNFMNLA PPLVFGANAA GNAVSGPSAL 1740 NNSITTSTAT SASGLGDTHL TSGVSSIPVD SGKATAVPPQ TQLNANANSQ LASNQKRART 1800 RITDDQLKIL RAHFDINNSP SEESIMEMSQ KANLPMKVVK HWFRNTLFKE RQRNKDSPYN 1860 FNNPPSTTLN LEEYERTGQA KVTPLNDTCS VAVTGPMTSS TISLPPSGNI NLSSKENATS 1920 KVLAAGKANA SGPVTFSATV PVSTPLSRPE STNSSGNISD YIGNNIFFGQ LGSKEQILPY 1980 SLDGQIKSEP QDDMIGATDF AYQTKQHSSF SFLKQQQDLV DPPEQCLTNQ NADTAQDQSL 2040 LAGSSLASNC QSQQQINIFE TKSESGSSDV LSRPPSPNSG AAGNVYGSMN DLLNQQLENM 2100 GSNMGPPKKM QIVGKTFEKN VAPMVTSGSV STQFESNSSN SSSSSSSTSG GKRANRTRFT 2160 DYQIKVLQEF FENNSYPKDS DLEYLSKLLL LSPRVIVVWF QNARQKQRKI YENQPNNTLF 2220 ENEETKKQNI NYACKKCNLV FQRYYELIRH QKNHCFKEEN NKKSAKAQIA AAQIAQNLSS 2280 EDSNSSMDIH HVGICPPGSA VASHTLSTPG SAAPLPGQYT QHSFGALPSP QHLFAKSSSL 2340 TDFSPSTTPT PPQRERSNSL DQIQRPPKFD CDKCELNFNQ LEKLREHQLL HLMNPGNICS 2400 DVGQNSNPEA NFGPFGSILQ SLQQAAAQQQ QQHHQQPPTK KRKYSDCSSN ADEMQSLSEL 2460 EASQKKHEYL YKYFMQNETS QEVKQQFLMQ QQQKKLEQGN ECDFELDFLT NFYQQNELKK 2520 VSNYDFLLQY YRTHEEAKSS QQHTFSSSKK PTIEFLLQYY QLNESKKFFQ LVASPQIIPD 2580 VPGYKPSLRI PKSTSDEAPY IGETSLEQAT ELQREKQDEQ LRIDRPSEEN DLSMNKNKVE 2640 NINNNNINVD QSNLTETNGG VPSVETKEEC TQESSLIAMD DENKYLCTRS KQKDDKEKSH 2700 YLHNLEDFLD ATMIENNSQT LTFNDDEKAC QKDELTQNSN AIEKRSSVSP VNVSSKQNKR 2760 LRTTILPEQL NFLYECYQSE SNPSRKMLEE ISKKVNLKKR VVQVWFQNSR AKDKKSRNQR 2820 HYAHISDDNS YDGSSGKEVY SDLRSNGITV DTDLETNLQD CQLCQVTQVN IRKHAFSVEH 2880 ISKMKKLLEQ TTELYAQSNG SGSEDNDSDR EKRFYNLSKA FLLQHVVTNA TSHAIHTARQ 2940 DSDVIAEGNC ILNYDTNGGD SKSHVQHNLP NEVVSEDARK IAGNQELMQQ LFNRNHITVI 3000 GGK 3003 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |