CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004261
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited 
Protein Synonyms/Alias
 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase 
Gene Name
 ARO3 
Gene Synonyms/Alias
 YDR035W; YD9673.07 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
87DYADRLAKISEKLSKubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP). 
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; Reference proteome; Stress response; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MFIKNDHAGD RKRLEDWRIK GYDPLTPPDL LQHEFPISAK GEENIIKARD SVCDILNGKD 60
DRLVIVIGPC SLHDPKAAYD YADRLAKISE KLSKDLLIIM RAYLEKPRTT VGWKGLINDP 120
DMNNSFQINK GLRISREMFI KLVEKLPIAG EMLDTISPQF LSDCFSLGAI GARTTESQLH 180
RELASGLSFP IGFKNGTDGG LQVAIDAMRA AAHEHYFLSV TKPGVTAIVG TEGNKDTFLI 240
LRGGKNGTNF DKESVQNTKK QLEKAGLTDD SQKRIMIDCS HGNSNKDFKN QPKVAKCIYD 300
QLTEGENSLC GVMIESNINE GRQDIPKEGG REGLKYGCSV TDACIGWEST EQVLELLAEG 360
VRNRRKALKK 370 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IDA:SGD.
 GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
 GO:0009423; P:chorismate biosynthetic process; TAS:SGD.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR006218; DAHP1/KDSA.
 IPR006219; DHAP_synth_1. 
Pfam
 PF00793; DAHP_synth_1 
SMART
  
PROSITE
  
PRINTS