CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020784
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 33A 
Protein Synonyms/Alias
  
Gene Name
 Vps33a 
Gene Synonyms/Alias
 Bf; Buff 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
77RLPAADVKNIIFLVRubiquitination[1]
318SVLSKKAKIISAAFEubiquitination[1]
337AKTVGEIKQFVSQLPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Endosome; Lysosome; Membrane; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 598 AA 
Protein Sequence
MAAHLSYGRV NLNVLREAVR RELREFLDKC AGSKAIVWDE YLTGPFGLIA QYSLLKEHEV 60
EKMFTLKGSR LPAADVKNII FLVRPRLELM DIIAENVLSE DRRGPTRDFH ILFVPRRSLL 120
CEQRLKDLGV LGSFIHREEY SLDLIPFDGD LLSMESEGAF KECYLEGDQT SLYHAAKGLM 180
TLQALYGTIP QIFGKGECAR QVANMMVRMK REFTGSQNSV FPVFDNLLLL DRNVDLLTPL 240
ASQLTYEGLI DEIYGIQNSY VKLPPEKFAP KKQGGGSGGK DLPTEAKKLQ LNSAEELYAE 300
IRDKNFNAVG SVLSKKAKII SAAFEERHNA KTVGEIKQFV SQLPHMQAAR GSLANHTSIA 360
ELIKDVTTSE DFFDKLTVEQ EFMSGIDTDK VNSYIEDCIA QKHPLIKVLR LVCLQSVCNS 420
GLKQKVLDYY RREILQTYGY EHILTLNNLE KAGLLKAQTG GRNNYPTIRK TLRLWMDDVN 480
EQNPTDISYV YSGYAPLSVR LAQLLSRPGW RSIEEVLRIL PGPHFEERQP LPTGLQKKRQ 540
PGENRVTLVF FLGGVTFAEI AALRFLSQLE DGGTEYVIAT TKLMNGNSWI EALMEKPF 598 
Gene Ontology
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
 GO:0043473; P:pigmentation; IMP:MGI.
 GO:0030220; P:platelet formation; IMP:MGI.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0048070; P:regulation of developmental pigmentation; IMP:MGI.
 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; ISA:MGI. 
Interpro
 IPR027482; Sec-1-like_dom2.
 IPR001619; Sec1-like.
 IPR027121; VPS33. 
Pfam
 PF00995; Sec1 
SMART
  
PROSITE
  
PRINTS