| Tag | Content |
|---|
| CPLM ID | CPLM-007046 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SPP41 |
Protein Synonyms/Alias | |
Gene Name | SPP41 |
Gene Synonyms/Alias | YDR464W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 668 | LRLTKSGKPKKPYRR | ubiquitination | [1] | | 859 | NTLKAAAKSQTAAGA | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Negative regulator of PRP3 and PRP4 genes. |
Sequence Annotation | REPEAT 171 190 UIM.
MOTIF 683 699 Nuclear localization signal (Potential).
MOD_RES 1014 1014 Phosphoserine.
MOD_RES 1067 1067 Phosphoserine.
CROSSLNK 981 981 Glycyl lysine isopeptide (Lys-Gly)
CROSSLNK 1154 1154 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Complete proteome; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1435 AA |
Protein Sequence | MAYDEDDGEI NFNELVGNLL SSHNQEGQEE GEVQGGEQEG DDFEKIYPTS ENIEPKHPDD 60
SQHMHNSPDQ NIEIPHFVDE EDELVSVVAN AVQNIDDEQA KPENHLENGS EHVTSDTADD 120
NHEKEQQQEW AHILQQEILK SDGEPLRENT ERRVSTSQHH PSQRTDDALD QDDENLRMAI 180
LESLQELNTN EEEEKEPEKH EHAAPNDKLS SKKSSKKKKK DKSKNRESSK DKSSKKSKSS 240
SHSKKHAKDR NKEKQSKPTN NENTLDLSNI LENLIHENDN AAIDTAKQTV DIQDNSHTDN 300
TNNEDVEAQA LVEATLKAFE NELLSSAPTE EPSQEQSIGP VSSRKAVEPP RKPTADDIPL 360
AMLQAFKPKK RPPQEKKKTK SKTSKAASTA NKSPASESTS KKKKKKKTVK ESNKSQEAYE 420
DDEFSRILAD MVNQVVNTSL KETSTHTATQ DNKLESESDF TSPVQSQYTT EDASTANDDS 480
LDLNQIMQNA MAMVFQNQND DEFDENIVED FNRGLGDLSV SDLLPHDNLS RMEKKSVPKS 540
SSKSEKKTAI SRRASKKASR DASSVELTEV PSKPKKPSKT EVSLEKKLRK KYVSIANEAA 600
SVARKKRWAK NKELKEKEKL ERQTAREERR HKKKLEKQRL AEEQEELKKI VERGPPYPPD 660
LRLTKSGKPK KPYRRWTPEE LLKRSQEAEK PRKVKKERKK KEKKMKVPSS ALKKIPLFNF 720
VKGNVQPSAR HRLNDIEGSL STIGLHKSPD GVRRILSRPK SEDHEWPLSD SSASQNYDAH 780
LKTVVHKEKI PFHPPWTIPS QPPFALPVAR RKKIPNIKKY RKRTNNSFRV SKEGTASTRN 840
RILPAILLPI INTLKAAAKS QTAAGATPEE ARKRLATIIQ HAKSTVIRAA LQARKNSMQA 900
AHSKGTTTEL ATTASRMKNP LKMIPIFNTS RVKQQLDKQL PARSAGTEIS SSESPDKATP 960
DPHSNSTIAG HTLKGVTTPI KIEDSDANVP PVSIAVSTIE PSQDKLELTK RAESVEPVEN 1020
NVETAKETQS VQEIKENVGT KASEEVTLTE DKTNGDPKNE KRILIESPVE KTDKKKPGEK 1080
IATDLNEDAS LSDKKDGDEK STLHSDAAQL TGNEPDSVNT TTGKPKLIDV SLKPLNEAKP 1140
KIPIIFPLKR PQIKPEVSVI NLVQNLVNTK IPEIKNESVD LGSNITDILS STITNILPEI 1200
TATDVKNYQY EDENVKYLKK TPRQVLNLDG LVPPSGRCIT KAKRVRRIKK LSADATTAPE 1260
ADGKANSESI TYTFDIPSPE EVQSKRSVVL KFAKARLTEA ELSCLKKEIN NVRKRRWREM 1320
NSTKNWEYDV KSRLKKRANA FFGEGESETK SKWIEERFQE KVSQEKYKDR LETTETQANN 1380
TKIVIDDKEI LNILAVNMNN LNKARCIEKD IQESFREEKL ASLQPKKKRK KSILH 1435 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |