CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035746
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Annexin 
Protein Synonyms/Alias
  
Gene Name
 Anxa6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
63QEICQSYKSLYGKDLacetylation[1]
68SYKSLYGKDLIADLKacetylation[1]
75KDLIADLKYELTGKFacetylation[1]
81LKYELTGKFERLIVNacetylation[1]
99PLAYCDAKEIKDAISacetylation[1]
102YCDAKEIKDAISGIGacetylation[1]
135HQLVAAYKDAYERDLubiquitination[2]
265ERLFKAMKGLGTRDNacetylation[1]
299IFRTKYEKSLYSMIKacetylation[1]
306KSLYSMIKNDTSGEYacetylation[1]
314NDTSGEYKKALLKLCacetylation[1]
354AVSRVELKGTVRAANacetylation[1]
370FNPDADAKALRKAMKacetylation[1]
377KALRKAMKGIGTDEAacetylation[1]
406QQIRQTFKSHFGRDLacetylation[1]
418RDLMADLKSEISGDLacetylation[1]
442PPAHYDAKQLKKAMEacetylation[1]
446YDAKQLKKAMEGAGTacetylation[1]
456EGAGTDEKALIEILAacetylation[1]
478RAINEAYKEDYHKSLacetylation[1]
478RAINEAYKEDYHKSLubiquitination[2]
483AYKEDYHKSLEDALSacetylation[1]
498SDTSGHFKRILISLAacetylation[1]
566RVFQEFIKKTNYDIEacetylation[1]
577YDIEHVIKKEMSGDVacetylation[1]
585KEMSGDVKDAFVAIVacetylation[1]
598IVQSVKNKPLFFADKacetylation[1]
605KPLFFADKLYKSMKGacetylation[1]
608FFADKLYKSMKGAGTacetylation[1]
611DKLYKSMKGAGTDEKacetylation[1]
618KGAGTDEKTLTRVMVacetylation[1]
642IRREFIEKYDKSLHQacetylation[1]
645EFIEKYDKSLHQAIEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Annexin; Calcium; Calcium/phospholipid-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 671 AA 
Protein Sequence
LLLSPQGAMY RGSVHDFADF DANQDAEALY TAMKGFGGDK ESILELITSR SNKQRQEICQ 60
SYKSLYGKDL IADLKYELTG KFERLIVNLM RPLAYCDAKE IKDAISGIGT DEKCLIEILA 120
SRTNEQIHQL VAAYKDAYER DLESDIIGDT SGHFQKMLVV LLQGTRENDD VVSEDLVQQD 180
VQDLYEAGEL KWGTDEAQFI YILGNRSKQH LRLVFDEYLK TTGKPIEASI RGELSGDFEK 240
LMLAVVKCIR STPEYFAERL FKAMKGLGTR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS 300
LYSMIKNDTS GEYKKALLKL CGGDDDAAGQ FFPEAAQVAY QMWELSAVSR VELKGTVRAA 360
NDFNPDADAK ALRKAMKGIG TDEATIIDII TQRSNAQRQQ IRQTFKSHFG RDLMADLKSE 420
ISGDLARLIL GLMMPPAHYD AKQLKKAMEG AGTDEKALIE ILATRTNAEI RAINEAYKED 480
YHKSLEDALS SDTSGHFKRI LISLATGNRE EGGENRDQAQ EDAQVRLLPI SDTPSGDKTS 540
LETRFMTVLC TRSYPHLRRV FQEFIKKTNY DIEHVIKKEM SGDVKDAFVA IVQSVKNKPL 600
FFADKLYKSM KGAGTDEKTL TRVMVSRSEI DLLNIRREFI EKYDKSLHQA IEGDTSGDFM 660
KALLALCGGE D 671 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW. 
Interpro
 IPR001464; Annexin.
 IPR018502; Annexin_repeat.
 IPR018252; Annexin_repeat_CS.
 IPR002393; AnnexinVI. 
Pfam
 PF00191; Annexin 
SMART
 SM00335; ANX 
PROSITE
 PS00223; ANNEXIN 
PRINTS
 PR00196; ANNEXIN.
 PR00202; ANNEXINVI.