| Tag | Content |
|---|
| CPLM ID | CPLM-006187 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar segregation protein PEP7 |
Protein Synonyms/Alias | Carboxypeptidase Y-deficient protein 7; Protein VAC1; Vacuolar protein sorting-associated protein 19; Vacuolar protein-targeting protein 19 |
Gene Name | PEP7 |
Gene Synonyms/Alias | VAC1; VPL21; VPS19; VPT19; YDR323C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 347 | SLKVETAKDSENTLD | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for vacuole segregation and vacuole protein sorting. Possibly part of a complex which tethers the vacuole membrane to microtubules, either directly or via kinesin or dynein-like motor proteins. Probably functions in several interorganelle traffic pathways. |
Sequence Annotation | ZN_FING 6 29 C2H2-type.
ZN_FING 72 137 FYVE-type 1.
ZN_FING 215 297 FYVE-type 2. |
Keyword | Complete proteome; Membrane; Metal-binding; Reference proteome; Repeat; Vacuole; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 515 AA |
Protein Sequence | MDLENVSCPI CLRKFDNLQA LNAHLDVEHG FNDNEDSLGS NDSRLVNGKQ KKARSVDSSA 60
QKLKRSHWEK FKKGKSCCHT CGRTLNNNIG AINCRKCGKL YCRRHLPNMI KLNLSAQYDP 120
RNGKWYNCCH DCFVTKPGYN DYGEVIDLTP EFFKVRNIKR EDKNLRLLQL ENRFVRLVDG 180
LITLYNTYSR SIIHNLKMNS EMSKLERTVT PWRDDRSVLF CNICSEPFGL LLRKHHCRLC 240
GMVVCDDANR NCSNEISIGY LMSAASDLPF EYNIQKDDLL HIPISIRLCS HCIDMLFIGR 300
KFNKDVRMPL SGIFAKYDSM QNISKVIDSL LPIFEDSLNS LKVETAKDSE NTLDPKNLND 360
LARLRHKLLN SFNLYNTLTR QLLSVEPQSH LERQLQNSIK IASAAYINEK ILPLKSLPAI 420
LNPEGHKTNE DGQKAEPEVK KLSQLMIENL TIKEVKELRE ELMVLKEQSY LIESTIQDYK 480
KQRRLEEIVT LNKNLEELHS RIHTVQSKLG DHGFN 515 |
Gene Ontology | GO:0010009; C:external side of endosome membrane; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006895; P:Golgi to endosome transport; IMP:SGD. GO:0006896; P:Golgi to vacuole transport; IGI:SGD. GO:0000011; P:vacuole inheritance; IMP:SGD. GO:0006904; P:vesicle docking involved in exocytosis; IMP:SGD. GO:0006906; P:vesicle fusion; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |