| Tag | Content |
|---|
| CPLM ID | CPLM-003118 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator HdfR |
Protein Synonyms/Alias | H-NS-dependent flhDC regulator |
Gene Name | hdfR |
Gene Synonyms/Alias | pssR; yifA; yifD; b4480; JW5607 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 63 | RLTAAGEKLLPYAET | acetylation | [1] | | 135 | AQRQSLVKQLHERQL | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. |
Sequence Annotation | DOMAIN 1 58 HTH lysR-type.
DNA_BIND 18 37 H-T-H motif (By similarity). |
Keyword | Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 279 AA |
Protein Sequence | MDTELLKTFL EVSRTRHFGR AAESLYLTQS AVSFRIRQLE NQLGVNLFTR HRNNIRLTAA 60
GEKLLPYAET LMSTWQAARK EVAHTSRHNE FSIGASASLW ECMLNQWLGR LYQNQDAHTG 120
LQFEARIAQR QSLVKQLHER QLDLLITTEA PKMDEFSSQL LGYFTLALYT SAPSKLKGDL 180
NYLRLEWGPD FQQHEAGLIG ADEVPILTTS SAELAQQQIA MLNGCTWLPV SWARKKGGLH 240
TVVDSTTLSR PLYAIWLQNS DKNALIRDLL KINVLDEVY 279 |
Gene Ontology | GO:0003677; F:DNA binding; IEA:HAMAP. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc. GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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