CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Perilipin-1 
Protein Synonyms/Alias
 Lipid droplet-associated protein; Perilipin A 
Gene Name
 Plin1 
Gene Synonyms/Alias
 Peri; Plin 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
379AQAVSSTKGRAMSLSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness (By similarity). 
Sequence Annotation
 MOD_RES 410 410 Phosphoserine.
 MOD_RES 460 460 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Lipid droplet; Lipid metabolism; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 517 AA 
Protein Sequence
MSMNKGPTLL DGDLPEQENV LQRVLQLPVV SGTCECFQKT YNSTKEAHPL VASVCNAYEK 60
GVQGASNLAA WSMEPVVRRL STQFTAANEL ACRGLDHLEE KIPALQYPPE KIASELKGTI 120
STRLRSARNS ISVPIASTSD KVLGATLAGC ELALGMAKET AEYAANTRVG RLASGGADLA 180
LGSIEKVVEF LLPPDKESAP SSGRQRTQKA PKAKPSLVRR VSTLANTLSR HTMQTTAWAL 240
KQGHSLAMWI PGVAPLSSLA QWGASAAMQV VSRRQSEVRV PWLHNLAASQ DESHDDQTDT 300
EGEETDDEEE EEESEAEENV LREVTALPNP RGLLGGVVHT VQNTLRNTIS AVTWAPAAVL 360
GTVGRILHLT PAQAVSSTKG RAMSLSDALK GVTDNVVDTV VHYVPLPRLS LMEPESEFRD 420
IDNPSAEAER KGSGARPASP ESTPRPGQPR GSLRSVRGLS APSCPGLDDK TEASARPGFL 480
AMPREKPARR VSDSFFRPSV MEPILGRAQY SQLRKKS 517 
Gene Ontology
 GO:0005811; C:lipid particle; TAS:Reactome.
 GO:0016042; P:lipid catabolic process; IMP:MGI. 
Interpro
 IPR004279; Perilipin. 
Pfam
 PF03036; Perilipin 
SMART
  
PROSITE
  
PRINTS