UniProt Accession

 H10_MOUSE; P10922; Q3UKC0 

Genbank Protein ID

 X13171; U18295; AK051213; AK077473; AK145675; AK146077; BC003830; BC011493; BC110361 

Genbank Nucleotide ID

 CAA31569.1; AAA69911.1; BAC34559.1; BAC36817.1; BAE26583.1; BAE26881.1; AAH03830.1; AAH11493.1; AAI10362.1 

Protein Name

 Histone H1.0 

Protein Synonyms/Alias

 Histone H1'; Histone H1(0); MyD196; Histone H1.0, N-terminally processed 

Gene Name

 H1f0 

Gene Synonyms/Alias

 H1fv 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
12	STSAPAAKPKRAKAS	acetylation	[1, 2]
27	KKSTDHPKYSDMIVA	acetylation	[3]
27	KKSTDHPKYSDMIVA	ubiquitination	[4]
40	VAAIQAEKNRAGSSR	ubiquitination	[4]
59	KYIKSHYKVGENADS	ubiquitination	[4]
82	LVTTGVLKQTKGVGA	acetylation	[3]
82	LVTTGVLKQTKGVGA	ubiquitination	[4]
85	TGVLKQTKGVGASGS	ubiquitination	[4]

Reference

 [1] Mass spectrometric mapping of linker histone H1 variants reveals multiple acetylations, methylations, and phosphorylation as well as differences between cell culture and tissue.
 Wisniewski JR, Zougman A, Krüger S, Mann M.
 Mol Cell Proteomics. 2007 Jan;6(1):72-87. [PMID: 17043054]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division. 

Sequence Annotation

 DOMAIN 24 97 H15.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 2 2 N-acetylthreonine; in Histone H1.0, N-  

Keyword

 Acetylation; Chromosome; Complete proteome; DNA-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 194 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.