CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026933
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ43235 fis, clone HCHON2004007, highly similar to Potential phospholipid-transporting ATPase IK (EC 3.6.3.13) 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
480PAGSSIFKGLRVPENubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 578 AA 
Protein Sequence
MGDSPGRGAP ERRHKAQPGR ARKYEWRPEG PTSMGSLGQR EDLQDEDRNS AFTWKVQANN 60
RAYNGQFKEK VILCWQRKKY KTNVIRTAKY NFYSFLPLNL YEQFHRVSNL FFLIIIILQS 120
IPDISTLPWF SLSTPMVCLL FIRATRDLVD DMGRHKSDRA INNRPCQILM GKSFKQKKWQ 180
DLCVGDVVCL RKDNIVPADM LLLASTEPSS LCYVETVDID GETNLKFRQA LMVTHKELAT 240
IKKMASFQGT VTCEAPNSRM HHFVGCLEWN DKKYSLDIGN LLLRGCRIRN TDTCYGLVIY 300
AGFDTKIMKN CGKIHLKRTK LDLLMNKLVV VIFISVVLVC LVLAFGFGFS VKEFKDHHYY 360
LSGVHGSSVA AESFFVFWSF LILLSVTIPM SMFILSEFIY LGNSVFIDWD VQMYYKPQDV 420
PAKARSTSLN DHLGQVEYIF SDKTGTLTQN ILTFNKCCIS GRVYGAAPTP ELPAGSSIFK 480
GLRVPENQSH VWPHAQHLRP NLNQGTVARW PGFLWRGPGK FFFFLRQSLT LSTQAGVQWC 540
NLGSLQSPPP GFRRFSWLSL PSGWDYRHLP PHLIFLYF 578 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004012; F:phospholipid-translocating ATPase activity; IEA:InterPro. 
Interpro
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR006539; ATPase_P-typ_Plipid-transp.
 IPR008250; ATPase_P-typ_transduc_dom_A. 
Pfam
 PF00122; E1-E2_ATPase 
SMART
  
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS