CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029748
UniProt Accession
Genbank Protein ID
 Z73420 
Genbank Nucleotide ID
  
Protein Name
 3-mercaptopyruvate sulfurtransferase 
Protein Synonyms/Alias
  
Gene Name
 MPST 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40DASWYLPKLGRDARRubiquitination[1, 2, 3]
146NLPLSSGKSQPAPAEubiquitination[3]
164QLDPAFIKTYEDIKEubiquitination[2, 3, 4]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 224 AA 
Protein Sequence
MASPQLCRAL VSAQWVAEAL RAPRAGQPLQ LLDASWYLPK LGRDARREFE ERHIPGAAFF 60
DIDQCSDRTS PYDHMLPGAE HFAEYAGRLG VGAATHVVIY DASDQGLYSA PRVWWMFRAF 120
GHHAVSLLDG GLRHWLRQNL PLSSGKSQPA PAEFRAQLDP AFIKTYEDIK ENLESRRFQV 180
VDSRATGRFR GTEPEPRDGS GSTAQAGVQW HNHGSLQPQP PGLR 224 
Gene Ontology
 GO:0004792; F:thiosulfate sulfurtransferase activity; IEA:InterPro. 
Interpro
 IPR001763; Rhodanese-like_dom.
 IPR001307; Thiosulphate_STrfase_CS. 
Pfam
 PF00581; Rhodanese 
SMART
 SM00450; RHOD 
PROSITE
 PS00380; RHODANESE_1
 PS50206; RHODANESE_3 
PRINTS