CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041389
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 SNW domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 SNW1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
153KTRVALEKSVSQKVAacetylation[1]
170MPVRAADKLAPAQYIacetylation[1, 2]
170MPVRAADKLAPAQYIubiquitination[1]
193VAFNSGAKQRVIRMVubiquitination[1, 3]
216PPRFKINKKIPRGPPubiquitination[3]
258ISNWKNAKGYTIPLDubiquitination[3]
266GYTIPLDKRLAADGRubiquitination[1, 3]
441DQAWRGGKDMAQSIYacetylation[1]
441DQAWRGGKDMAQSIYubiquitination[3]
456RPSKNLDKDMYGDDLubiquitination[3]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 571 AA 
Protein Sequence
MALTSFLPAP TQLSQDQLEA EEKARSQRSR QTSLVSSRRE PPPYGYRKGW IPRLLEDFGD 60
GGAFPEIHVA QYPLDMGRKK KMSNALAIQV DSEGKIKYDA IARQGQSKDK VIYSKYTDLV 120
PKEVMNADDP DLQRPDEEAI KEITEKTRVA LEKSVSQKVA AAMPVRAADK LAPAQYIRYT 180
PSQQGVAFNS GAKQRVIRMV EMQKDPMEPP RFKINKKIPR GPPSPPAPVM HSPSRKMTVK 240
EQQEWKIPPC ISNWKNAKGY TIPLDKRLAA DGRGLQTVHI NENFAKLAEA LYIADRKARE 300
AVEMRAQVER KMAQKEKEKH EEKLREMAQK ARERRAGIKT HVEKEDGEAR ERDEIRHDRR 360
KERQHDRNLS RAAPDKRSKL QRNENRDISE VIALGVPNPR TSNEVQYDQR LFNQSKGMDS 420
GFAGGEDEIY NVYDQAWRGG KDMAQSIYRP SKNLDKDMYG DDLEARIKTN RCQAIQLNFS 480
VYTGESKVVH SFFSFSLDLF PTRSFLVQTV DREAEKDQCS LRKILLVWTS FWKKPNSMVA 540
LKDPQIAAAP RNTSMKARRG GRNRHRSLQS E 571 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005681; C:spliceosomal complex; IEA:InterPro.
 GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro. 
Interpro
 IPR017862; SKI-int_prot_SKIP.
 IPR004015; SKI-int_prot_SKIP_SNW-dom. 
Pfam
 PF02731; SKIP_SNW 
SMART
  
PROSITE
  
PRINTS