CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044733
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Usp13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
637IVIPDDSKDRLMNQLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 857 AA 
Protein Sequence
MQRRGALFSV PGGGGKMAAG DLGELLVPHM PTIRVPRSGD RVYKNECAFS YDSPNSEGGL 60
YVCMNTFLAF GREHVERHFR KTGQSVYMHL KRHMREVRGA SGGALPKRRN SKIFLDLDMD 120
DDLNSDDYEY EDEAKLVIFP DHYEIALPNI EELPALVTIA CDAVLSSKSP YRKQDPDTWE 180
NEVPVSKYAN NLVQLDNGVR IPPSGWKCAR CDLRENLWLN LTDGSVLCGK WFFDSSGGNG 240
HALEHYRDMG YPLAVKLGTI TPDGADVYSF QEEGPVSDPH LAKHLAHFGI DMLHTQGTEN 300
GLRDNDIKPR VSEWEVIQES GTKLKPMYGP GYTGLKNLGN SCYLSSVMQA IFSIPEFQRA 360
YVGNLPRIFD YSPLDPTQDF NTQMTKLGHG LLSGQYSKPP VKSELIEQVM KEEHKPQQNG 420
ISPRMFKAFV SKSHPEFSSN RQQDAQEFFL HLVNLVERNR IGSENPSDVF RFLVEERIQC 480
CQTRKVRYTE RVDYLMQLPV AMEAATNKDE LITYELMRRE AEANRRPLPE LVRAKIPFSA 540
CLQAFAEPDN VDDFWSSALQ AKSAGVKTSR FASFPEYLVV QIKKFTFGLD WVPRKFDVSI 600
DMPDLLDISH LRARGLQPGE EELPDISPPI VIPDDSKDRL MNQLIDPSDI DESSVMQLAE 660
MGFPLEACRK AVYFTGNTGA EVAFNWIIVH MEEPDFAEPL AIPGYGGAGA SVFGATGLDN 720
QPPEEIVAII TSMGFQRNQA VQALQATNHN LERALDWIFS HPEFEEDSDF VIEMENNANA 780
NIVSEAKPEG PRVKDGSGMY ELFAFISHMG TSTMSGHYVC HIKKEGRWVI YNDHKVCASE 840
RPPKDLGYMY FYRRIPS 857 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19.
 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N.
 IPR015940; UBA/transl_elong_EF1B_N_euk.
 IPR016652; Ubiquitinyl_hydrolase.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001607; Znf_UBP. 
Pfam
 PF00627; UBA
 PF00443; UCH
 PF02148; zf-UBP 
SMART
 SM00165; UBA
 SM00290; ZnF_UBP 
PROSITE
 PS50030; UBA
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3
 PS50271; ZF_UBP 
PRINTS