CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005987
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syndecan-4 
Protein Synonyms/Alias
 SYND4; Amphiglycan; Ryudocan core protein 
Gene Name
 SDC4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
190GKKPIYKKAPTNEFYubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Cell surface proteoglycan that bears heparan sulfate. 
Sequence Annotation
 CARBOHYD 39 39 O-linked (Xyl...) (heparan sulfate) (By
 CARBOHYD 61 61 O-linked (Xyl...) (heparan sulfate)
 CARBOHYD 63 63 O-linked (Xyl...) (heparan sulfate)  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Glycoprotein; Heparan sulfate; Membrane; Polymorphism; Proteoglycan; Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MAPARLFALL LFFVGGVAES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL 60
SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE 120
ESEDVSNKVS MSSTVQGSNI FERTEVLAAL IVGGIVGILF AVFLILLLMY RMKKKDEGSY 180
DLGKKPIYKK APTNEFYA 198 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0043034; C:costamere; IEA:Compara.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0005796; C:Golgi lumen; TAS:Reactome.
 GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
 GO:0043202; C:lysosomal lumen; TAS:Reactome.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0070053; F:thrombospondin receptor activity; IMP:BHF-UCL.
 GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
 GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
 GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
 GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
 GO:0007603; P:phototransduction, visible light; TAS:Reactome.
 GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Compara.
 GO:0045860; P:positive regulation of protein kinase activity; IEA:Compara.
 GO:0051496; P:positive regulation of stress fiber assembly; IEA:Compara.
 GO:0001523; P:retinoid metabolic process; TAS:Reactome.
 GO:0001657; P:ureteric bud development; IEA:Compara. 
Interpro
 IPR003585; Neurexin-like.
 IPR001050; Syndecan. 
Pfam
 PF01034; Syndecan 
SMART
 SM00294; 4.1m 
PROSITE
 PS00964; SYNDECAN 
PRINTS