| Tag | Content |
|---|
| CPLM ID | CPLM-014308 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform |
Protein Synonyms/Alias | PP2A B subunit isoform B'-epsilon; PP2A B subunit isoform B56-epsilon; PP2A B subunit isoform PR61-epsilon; PP2A B subunit isoform R5-epsilon |
Gene Name | Ppp2r5e |
Gene Synonyms/Alias | Kiaa4006 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 41 | SQFRSQGKPIELTPL | ubiquitination | [1] | | 219 | GLRAFIRKQINNIFL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Interacts with cyclin G in vitro. |
Sequence Annotation | MOD_RES 30 30 Phosphoserine (By similarity).
MOD_RES 32 32 Phosphoserine (By similarity).
MOD_RES 34 34 Phosphoserine (By similarity). |
Keyword | Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 467 AA |
Protein Sequence | MSSAPTTPPS VDKVDGFSRK SVRKARQKRS QSSSQFRSQG KPIELTPLPL LKDVPTSEQP 60
ELFLKKLQQC CVIFDFMDTL SDLKMKEYKR STLNELVDYI TISRGCLTEQ TYPEVVRMVS 120
CNIFRTLPPS DSNEFDPEED EPTLEASWPH LQLVYEFFIR FLESQEFQPS IAKKYIDQKF 180
VLQLLELFDS EDPRERDYLK TVLHRIYGKF LGLRAFIRKQ INNIFLRFVY ETEHFNGVAE 240
LLEILGSIIN GFALPLKAEH KQFLVKVLIP LHTVRSLSLF HAQLAYCIVQ FLEKDPSLTE 300
PVIRGLMKFW PKTCSQKEVM FLGELEEILD VIEPSQFVKI QEPLFKQIAK CVSSPHFQVA 360
ERALYYWNNE YIMSLIEENS NVILPIMFSS LYRISKEHWN PAIVALVYNV LKAFMEMNST 420
MFDELTATYK SDRQREKKKE KEREELWKKL EDLELKRGLR RDGIIPT 467 |
Gene Ontology | GO:0005737; C:cytoplasm; TAS:MGI. GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara. GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro. GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |