CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial peptide methionine sulfoxide reductase 
Protein Synonyms/Alias
 Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase; Protein-methionine-S-oxide reductase; PMSR 
Gene Name
 Msra 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
179KSKEEYQKVLSKHGFacetylation[1]
183EYQKVLSKHGFGPITacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). 
Sequence Annotation
 MOD_RES 183 183 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Mitochondrion; Oxidoreductase; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 233 AA 
Protein Sequence
MLSASRRTLQ LLSSSIPVRM MGDSSSKVIS AEEALPGRTE SIPVAAKHHV SGNRTVEPFP 60
EGTQMAVFGM GCFWGAERKF WLLKGVYSTQ VGFAGGYTRN PTYKEVCSEK TGHAEVVRVV 120
YRPEHVSFEE LLKVFWENHD PTQGMRQGND CGTQYRSAVY PTSAVQMEAA LKSKEEYQKV 180
LSKHGFGPIT TDIREGQVFY YAEDYHQQYL SKNPDGYCGL GGTGVSCPTA IKK 233 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0008113; F:peptide-methionine (S)-S-oxide reductase activity; IDA:RGD.
 GO:0007568; P:aging; IDA:RGD. 
Interpro
 IPR002569; Met_Sox_Rdtase_MsrA. 
Pfam
 PF01625; PMSR 
SMART
  
PROSITE
  
PRINTS