CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040597
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Methyltransferase-like protein 7A 
Protein Synonyms/Alias
  
Gene Name
 METTL7A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34LWSWICKKWFPYFLVubiquitination[1]
71EFAGPSGKLSLLEVGubiquitination[2]
105DPNPNFEKFLIKSIAubiquitination[3]
109NFEKFLIKSIAENRHubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 180 AA 
Protein Sequence
MELTIFILRL AIYILTFPLY LLNFLGLWSW ICKKWFPYFL VRFTVIYNEQ MASKKRELFS 60
NLQEFAGPSG KLSLLEVGCG TGANFKFYPP GCRVTCIDPN PNFEKFLIKS IAENRHLQFE 120
RFVVAAGENM HQVADGSVDV VVCTLVLCSV KNQERILREV CRVLRPGGAF YFMEHVAAEC 180 
Gene Ontology
 GO:0008168; F:methyltransferase activity; IEA:InterPro.
 GO:0032259; P:methylation; IEA:GOC. 
Interpro
 IPR013216; Methyltransf_11. 
Pfam
 PF08241; Methyltransf_11 
SMART
  
PROSITE
  
PRINTS