CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003732
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S24-A 
Protein Synonyms/Alias
 RP50 
Gene Name
 RPS24A 
Gene Synonyms/Alias
 RPS24EA; YER074W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
11AVTIRTRKVISNPLLubiquitination[1]
21SNPLLARKQFVVDVLacetylation[2]
21SNPLLARKQFVVDVLubiquitination[1, 3]
37PNRANVSKDELREKLacetylation[2]
43SKDELREKLAEVYKAacetylation[2]
43SKDELREKLAEVYKAubiquitination[1]
49EKLAEVYKAEKDAVSacetylation[2]
49EKLAEVYKAEKDAVSubiquitination[1]
52AEVYKAEKDAVSVFGacetylation[2]
52AEVYKAEKDAVSVFGubiquitination[1]
68RTQFGGGKSVGFGLVacetylation[2]
68RTQFGGGKSVGFGLVubiquitination[1]
83YNSVAEAKKFEPTYRacetylation[2]
83YNSVAEAKKFEPTYRubiquitination[1]
84NSVAEAKKFEPTYRLacetylation[2]
84NSVAEAKKFEPTYRLubiquitination[1]
99VRYGLAEKVEKASRQacetylation[2]
99VRYGLAEKVEKASRQubiquitination[1]
117QKKNRDKKIFGTGKRubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylserine.
 MOD_RES 14 14 Phosphoserine.
 MOD_RES 56 56 Phosphoserine.  
Keyword
 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 135 AA 
Protein Sequence
MSDAVTIRTR KVISNPLLAR KQFVVDVLHP NRANVSKDEL REKLAEVYKA EKDAVSVFGF 60
RTQFGGGKSV GFGLVYNSVA EAKKFEPTYR LVRYGLAEKV EKASRQQRKQ KKNRDKKIFG 120
TGKRLAKKVA RRNAD 135 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IBA:RefGenome.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005730; C:nucleolus; IBA:RefGenome.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; NAS:SGD.
 GO:0002181; P:cytoplasmic translation; NAS:SGD.
 GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD.
 GO:0006414; P:translational elongation; IBA:RefGenome. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR012678; Ribosomal_L23/L15e_core_dom.
 IPR001976; Ribosomal_S24e.
 IPR018098; Ribosomal_S24e_CS. 
Pfam
 PF01282; Ribosomal_S24e 
SMART
  
PROSITE
 PS00529; RIBOSOMAL_S24E 
PRINTS