CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear pore complex protein Nup107 
Protein Synonyms/Alias
 cDNA FLJ58739, highly similar to Nuclear pore complex protein Nup107 
Gene Name
 NUP107 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
56CILGTGGKSPRLTQSubiquitination[1, 2, 3]
172RATPGLQKFSKTASMubiquitination[2, 3, 4, 5]
276ENTLHTLKQRQLTSYubiquitination[2, 3, 5, 6]
303PDAPIRQKMPLDDLDubiquitination[1, 2, 3, 5]
353AATLEGWKLYHDPNVubiquitination[2, 5, 6]
379NPYRRIWKISCWRMAubiquitination[1, 2]
462GANWTLEKVFEELQAubiquitination[2]
472EELQATDKKRVLEENubiquitination[2, 5]
473ELQATDKKRVLEENQubiquitination[2, 3]
597HHCLELAKEADLDVAubiquitination[2, 6]
608LDVATITKTVVENIRubiquitination[2, 5, 6, 7]
616TVVENIRKKDNGEFSubiquitination[2]
661AQRAEALKQGNAIMRubiquitination[1, 2, 5, 6, 7]
680SKKHEAAKEVFVKIPubiquitination[2, 5]
685AAKEVFVKIPQDSIAubiquitination[6]
744HMNSVPQKPALIPQPubiquitination[2, 4, 5, 7]
756PQPTFTEKVAHEHKEubiquitination[2]
785DALTADVKEKMYNVLubiquitination[3, 5, 6]
865KLYLVFSKEELRKLLubiquitination[4]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [6] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [7] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 896 AA 
Protein Sequence
MKILVILHQE TRLSLELLAH FDSLVLSTNL LFIVTPTSRS LLRQPDISCI LGTGGKSPRL 60
TQSSGFFGNL SMVTNLDDSN WAAAFSSQRS GLFTNTEPHS ITEDVTISAV MLREDDPGEA 120
ASMSMFSDFL QSFLKHSSST VFDLVEEYEN ICGSQVNILS KIVSRATPGL QKFSKTASML 180
WLLQQEMVTW RLLASLYRDR IQSALEEESV FAVTAVNASE KTVVEALFQR DSLVRQSQLV 240
VDWLESIAKD EIGEFSDNIE FYAKSVYWEN TLHTLKQRQL TSYVGSVRPL VTELDPDAPI 300
RQKMPLDDLD REDEVRLLKY LFTLIRAGMT EEAQRLCKRC GQAWRAATLE GWKLYHDPNV 360
NGGTELEPVE GNPYRRIWKI SCWRMAEDEL FNRYERAIYA ALSGNLKQLL PVCDTWEDTV 420
WAYFRVMVDS LVEQEIQTSV ATLDETEELP REYLGANWTL EKVFEELQAT DKKRVLEENQ 480
EHYHIVQKFL ILGDIDGLMD EFSKWLSKSR NNLPGHLLRF MTHLILFFRT LGLQTKEEVS 540
IEVLKTYIQL LIREKHTNLI AFYTCHLPQD LAVAQYALFL ESVTEFEQRH HCLELAKEAD 600
LDVATITKTV VENIRKKDNG EFSHHDLAPA LDTGTTEEDR LKIDVIDWLV FDPAQRAEAL 660
KQGNAIMRKF LASKKHEAAK EVFVKIPQDS IAEIYNQCEE QGMESPLPAE DDNAIREHLC 720
IRAYLEAHET FNEWFKHMNS VPQKPALIPQ PTFTEKVAHE HKEKKYEMDF GIWKGHLDAL 780
TADVKEKMYN VLLFVDGGWM VDVREDAKED HERTHQMVLL RKLCLPMLCF LLHTILHSTG 840
QYQECLQLAD MVSSERHKLY LVFSKEELRK LLQKLRESSL MLLDQGLDPL GYEIQL 896 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:InterPro.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR007252; Nup84_Nup100. 
Pfam
 PF04121; Nup84_Nup100 
SMART
  
PROSITE
  
PRINTS