| Tag | Content |
|---|
| CPLM ID | CPLM-031354 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Epidermal growth factor receptor kinase substrate 8 |
Protein Synonyms/Alias | Epidermal growth factor receptor pathway substrate 8, isoform CRA_b; cDNA FLJ50272, highly similar to Epidermal growth factor receptor kinase substrate 8; cDNA, FLJ79033, highly similar to Epidermal growth factor receptor kinase substrate 8; cDNA, FLJ79138, highly similar to Epidermal growth factor receptor kinase substrate 8 |
Gene Name | EPS8 |
Gene Synonyms/Alias | hCG_1811074 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 521 | YSQITVQKAALEDSS | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Kinase; Receptor; Reference proteome; SH3 domain; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 562 AA |
Protein Sequence | MMAARIDRDV QILNHILDDI EFFITKLQKA AEAFSELSKR KKNKKGKRKG PGEGVLTLRA 60
KPPPPDEFLD CFQKFKHGFN LLAKLKSHIQ NPSAADLVHF LFTPLNMVVQ ATGGPELASS 120
VLSPLLNKDT IDFLNYTVNG DERQLWMSLG GTWMKARAEW PKEQFIPPYV PRFRNGWEPP 180
MLNFMGATME QDLYQLAESV ANVAEHQRKQ EIKRLSTEHS SVSEYHPADG YAFSSNIYTR 240
GSHLDQGEAA VAFKPTSNRH IDRNYEPLKT QPKKYAKSKY DFVARNNSEL SVLKDDILEI 300
LDDRKQWWKV RNASGDSGFV PNNILDIVRP PESGLGRADP PYTHTIQKQR MEYGPRPADT 360
PPAPSPPPTP APVPVPLPPS TPAPVPVSKV PANITRQNSS SSDSGGSIVR DSQRHKQLPV 420
DRRKSQMEEV QDELIHRLTI GRSAAQKKFH VPRQNVPVIN ITYDSTPEDV KTWLQSKGFN 480
PVTVNSLGVL NGAQLFSLNK DELRTVCPEG ARVYSQITVQ KAALEDSSGS SELQEIMRRR 540
QEKISAAASD SGVESFDEGS SH 562 |
Gene Ontology | GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IEA:Compara. GO:0014069; C:postsynaptic density; IEA:Compara. GO:0016301; F:kinase activity; IEA:UniProtKB-KW. GO:0031532; P:actin cytoskeleton reorganization; IEA:Compara. GO:0051017; P:actin filament bundle assembly; IEA:Compara. GO:0008344; P:adult locomotory behavior; IEA:Compara. GO:0048149; P:behavioral response to ethanol; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |