CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038111
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription factor 7-like 1 
Protein Synonyms/Alias
  
Gene Name
 Tcf3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
173GLADTQPKKVRKVPPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 650 AA 
Protein Sequence
MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG LEDRPSSGSW 60
GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG GKGSERNAYA TFGRDTSVGT 120
LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY YPSFPSNPRR RAADGGLADT QPKKVRKVPP 180
GLPSSVYPPS SGDSYSRDAA AYPSAKTPSS AYPSPFYVAD GSLHPSAELW STPSQVGFGP 240
MLGDGSSPLP LAPGSSSVGS GTFGGLQQQD RMGYQLHGSE VNGSLPAVSS FSAAPGTYSG 300
TSGHTPPVSG AAAESLLGTR GTTASSSGDA LGKALASIYS PDHSSNNFSP SPSTPVGSPQ 360
GLPGTSQWPR AGAPSALSPN YDAGLHGLQS KMEDRLDEAI HVLRSHAVGT ASDLHGLLPG 420
HGALTTSFTG PMSLGGRHAG LVGGSHPEEG LTSGASLLHN HASLPSQPSS LPDLSQRPPD 480
SYSGLGRAGT TAGASEIKRE EKEDEEIASV ADAEEDKKDL KVPRTRTSST DEVLSLEEKD 540
LRDRERRMAN NARERVRVRD INEAFRELGR MCQLHLKSDK AQTKLLILQQ AVQVILGLEQ 600
QVRERNLNPK AACLKRREEE KVSGVVGDPQ LALSAAHPGL GEAHNPAGHL 650 
Gene Ontology
 GO:0000788; C:nuclear nucleosome; IDA:MGI.
 GO:0005667; C:transcription factor complex; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0046982; F:protein heterodimerization activity; ISO:MGI.
 GO:0042803; F:protein homodimerization activity; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.
 GO:0048468; P:cell development; IGI:MGI.
 GO:0043966; P:histone H3 acetylation; IMP:MGI.
 GO:0043967; P:histone H4 acetylation; IMP:MGI.
 GO:0033152; P:immunoglobulin V(D)J recombination; IMP:MGI.
 GO:0001779; P:natural killer cell differentiation; IGI:MGI.
 GO:0048541; P:Peyer's patch development; IGI:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0050821; P:protein stabilization; IDA:MGI.
 GO:0042493; P:response to drug; IMP:MGI.
 GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
 GO:0033077; P:T cell differentiation in thymus; IMP:MGI. 
Interpro
 IPR011598; bHLH_dom. 
Pfam
 PF00010; HLH 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS