| Tag | Content |
|---|
| CPLM ID | CPLM-007714 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Afamin |
Protein Synonyms/Alias | Alpha-albumin; Alpha-Alb |
Gene Name | AFM |
Gene Synonyms/Alias | ALB2; ALBA |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 332 | DLSLREGKFTDSENV | glycation | [1] |
|
Reference | [1] Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes. Zhang Q, Tang N, Schepmoes AA, Phillips LS, Smith RD, Metz TO. J Proteome Res. 2008 May;7(5):2025-32. [ PMID: 18396901] |
Functional Description | Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier (By similarity). |
Sequence Annotation | DOMAIN 22 210 Albumin 1.
DOMAIN 211 403 Albumin 2.
DOMAIN 404 599 Albumin 3.
CARBOHYD 33 33 N-linked (GlcNAc...).
CARBOHYD 109 109 N-linked (GlcNAc...) (complex).
CARBOHYD 383 383 N-linked (GlcNAc...) (complex); atypical.
CARBOHYD 402 402 N-linked (GlcNAc...) (complex).
CARBOHYD 488 488 N-linked (GlcNAc...).
DISULFID 77 86 By similarity.
DISULFID 99 114 By similarity.
DISULFID 113 124 By similarity.
DISULFID 148 193 By similarity.
DISULFID 192 201 By similarity.
DISULFID 224 270 By similarity.
DISULFID 269 277 By similarity.
DISULFID 289 303 By similarity.
DISULFID 302 313 By similarity.
DISULFID 340 385 By similarity.
DISULFID 384 393 By similarity.
DISULFID 416 462 By similarity.
DISULFID 461 470 By similarity.
DISULFID 483 499 By similarity.
DISULFID 498 509 By similarity.
DISULFID 536 581 By similarity.
DISULFID 580 589 By similarity. |
Keyword | Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Polymorphism; Reference proteome; Repeat; Secreted; Signal; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 599 AA |
Protein Sequence | MKLLKLTGFI FFLFFLTESL TLPTQPRDIE NFNSTQKFIE DNIEYITIIA FAQYVQEATF 60
EEMEKLVKDM VEYKDRCMAD KTLPECSKLP NNVLQEKICA MEGLPQKHNF SHCCSKVDAQ 120
RRLCFFYNKK SDVGFLPPFP TLDPEEKCQA YESNRESLLN HFLYEVARRN PFVFAPTLLT 180
VAVHFEEVAK SCCEEQNKVN CLQTRAIPVT QYLKAFSSYQ KHVCGALLKF GTKVVHFIYI 240
AILSQKFPKI EFKELISLVE DVSSNYDGCC EGDVVQCIRD TSKVMNHICS KQDSISSKIK 300
ECCEKKIPER GQCIINSNKD DRPKDLSLRE GKFTDSENVC QERDADPDTF FAKFTFEYSR 360
RHPDLSIPEL LRIVQIYKDL LRNCCNTENP PGCYRYAEDK FNETTEKSLK MVQQECKHFQ 420
NLGKDGLKYH YLIRLTKIAP QLSTEELVSL GEKMVTAFTT CCTLSEEFAC VDNLADLVFG 480
ELCGVNENRT INPAVDHCCK TNFAFRRPCF ESLKADKTYV PPPFSQDLFT FHADMCQSQN 540
EELQRKTDRF LVNLVKLKHE LTDEELQSLF TNFANVVDKC CKAESPEVCF NEESPKIGN 599 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |