UniProt Accession

 TNNI1_MOUSE; Q9WUZ5 

Genbank Protein ID

 AJ242874; AK012258; BC023170 

Genbank Nucleotide ID

 CAB48403.1; BAB28123.1; AAH23170.1 

Protein Name

 Troponin I, slow skeletal muscle 

Protein Synonyms/Alias

 Troponin I, slow-twitch isoform 

Gene Name

 Tnni1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
131	LRALLGSKHKVSMDL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. 

Sequence Annotation

 REGION 1 48 Involved in binding TNC.
 REGION 97 118 Involved in binding TNC and actin.  

Keyword

 Actin-binding; Calcium; Complete proteome; Metal-binding; Muscle protein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0005861; C:troponin complex; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI. 

Interpro

 IPR001978; Troponin. 

Pfam

 PF00992; Troponin 

SMART

  

PROSITE

  

PRINTS