CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031139
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin-6 
Protein Synonyms/Alias
 cDNA FLJ57566, highly similar to Syntaxin-6 
Gene Name
 STX6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
38WSTGTTDKYGRLDREubiquitination[1, 2, 3, 4]
83SGSIGVLKNMSQRIGubiquitination[3, 4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 154 AA 
Protein Sequence
MKDQMSTSSV QALAERKNRQ ALLGDSGSQN WSTGTTDKYG RLDRELQRAN SHFIEEQQAQ 60
QQLIVEQQDE QLELVSGSIG VLKNMSQRIG GELEEQAVML EDFSHELEST QSRLDNVMKK 120
LAKVSHMTSD RRQWCAIAIL FAVLLVVLIL FLVL 154 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:Compara.
 GO:0032588; C:trans-Golgi network membrane; IEA:Compara.
 GO:0007032; P:endosome organization; IEA:Compara.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:Compara. 
Interpro
 IPR006012; Syntaxin/epimorphin_CS.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS