UniProt Accession

 D6RCE2_HUMAN; D6RCE2 

Genbank Protein ID

 AC090071 

Genbank Nucleotide ID

  

Protein Name

 Tetratricopeptide repeat protein 37 

Protein Synonyms/Alias

  

Gene Name

 TTC37 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
66	YESVDKQKWCDVCKK	ubiquitination	[1]
286	LSCSQALKIVDNLGA	ubiquitination	[1]
344	IPGLLVLKSLAYRNK	ubiquitination	[1, 2]
393	KDYLQAEKCFQRALE	ubiquitination	[1]
548	AALRADPKDFNCWES	ubiquitination	[1]
571	GGYTTALKSFTKASE	ubiquitination	[3]
599	AIQQILGKYKEAVAQ	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 611 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR006597; Sel1-like.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 

Pfam

 PF08238; Sel1
 PF13174; TPR_6 

SMART

 SM00028; TPR 

PROSITE

 PS50005; TPR
 PS50293; TPR_REGION 

PRINTS