CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038355
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Abcc4 
Protein Synonyms/Alias
  
Gene Name
 Abcc4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
54VLPEDRSKHLGEELQubiquitination[1]
515IKACALKKDLQLLEDubiquitination[1]
622GTYTEFLKSGVDFGSubiquitination[1]
1278KMVQQLGKGEAAALTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1325 AA 
Protein Sequence
MLPVHTEVKP NPLQDANLCS RVFFWWLNPL FKTGHKRRLE EDDMFSVLPE DRSKHLGEEL 60
QRYWDKELLR AKKDSRKPSL TKAIIKCYWK SYLILGIFTL IEEGTRVVQP LFLGKIIEYF 120
EKYDPDDSVA LHTAYGYAAV LSMCTLILAI LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR 180
LSNSAMGKTT TGQIVNLLSN DVNKFDQVTI FLHFLWAGPL QAIAVTVLLW VEIGISCLAG 240
LAVLVILLPL QSCIGKLFSS LRSKTAAFTD ARIRTMNEVI TGMRIIKMYA WEKSFADLIA 300
NLRKKEISKI LGSSYLRGMN MASFFIANKV ILFVTFTSYV LLGNEITASH VFVAMTLYGA 360
VRLTVTLFFP SAIERGSEAI VSIRRIKNFL LLDELPQRKA HVPSDGKAIV HVQDFTAFWD 420
KALDSPTLQG LSFIARPGEL LAVVGPVGAG KSSLLSAVLG ELPPASGLVS VHGRIAYVSQ 480
QPWVFSGTVR SNILFGKKYE KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGATLSGGQK 540
ARVNLARAVY QDADIYLLDD PLSAVDAEVG KHLFQLCICQ ALHEKITILV THQLQYLKAA 600
SHILILKDGE MVQKGTYTEF LKSGVDFGSL LKKENEEAEP STAPGTPTLR KRTFSEASIW 660
SQQSSRPSLK DGAPEGQDAE NTQAVQPEES RSEGRIGFKA YKNYFSAGAS WFFIIFLVLL 720
NMVGQVFYVL QDWWLSHWAN KQGALNNTRN ANGNITETLD LSWYLGIYAG LTAVTVLFGI 780
ARSLLVFYIL VNASQTLHNR MFESILKAPV LFFDRNPIGR ILNRFSKDIG HMDDLLPLTF 840
LDFIQTLLLV VSVIAVAAAV IPWILIPLVP LSVVFLVLRR YFLETSRDVK RLESTTRSPV 900
FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV RLDAICAIFV 960
IVVAFGSLVL AKTLNAGQVG LALSYALTLM GMFQWSVRQS AEVENMMISV ERVIEYTDLE 1020
KEAPWECKKR PPPGWPHEGV IVFDNVNFTY SLDGPLVLKH LTALIKSREK VGIVGRTGAG 1080
KSSLISALFR LSEPEGKIWI DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE 1140
HTDEELWRAL EEVQLKEAIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILKNNRILII 1200
DEATANVDPR TDELIQQKIR EKFAQCTVLT IAHRLNTIID SDKIMVLDSG RLKEYDEPYV 1260
LLQNPESLFY KMVQQLGKGE AAALTETAKQ VYFRRNYPDI TFTSPAVMNT SNGQPSALTI 1320
FETAL 1325 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0031088; C:platelet dense granule membrane; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
 GO:0015238; F:drug transmembrane transporter activity; TAS:MGI.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS